A new MRI approach could spare patients unnecessary lung biopsies
NCT ID NCT07768046
First seen Aug 17, 2026 · Last updated Aug 17, 2026
Summary
This study explores whether a special MRI scan, done without any contrast dye, can tell the difference between benign and cancerous lung nodules that were flagged as suspicious on a routine lung cancer screening CT. Adults aged 50 to 80 with a history of heavy smoking and a Lung-RADS 4 nodule will receive one additional MRI scan. The MRI results will be compared with the final diagnosis from biopsy or long-term follow-up to see how accurate the scan is.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Multiparametric chest MRI with diffusion-weighted imaging (no contrast)
- What this could lead to
- If successful, this could offer a safer, contrast-free imaging method to help doctors decide which lung nodules need biopsy, reducing unnecessary invasive procedures.
- What could go wrong
- This is a small pilot study with only 30 participants, so results may not be definitive. The MRI might not reliably distinguish all benign from malignant nodules, and its accuracy needs confirmation in larger trials.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LUNG CANCER SCREENING are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UF Health Shands Hospital
Gainesville, Florida, 32610, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a simple CT scan catch lung cancer earlier in kuwait?
- Light-Based blood test may spot lung cancer early
- Get up and eat: a new approach to speed lung surgery recovery?
- Repositioning arms during lung surgery may cut Post-Op shoulder pain
- Can a Heat-and-Freeze treatment plus a vaccine outsmart pancreatic cancer?
- One drop, many cancers? a rapid test aims to spot cancer signals in blood, urine, or saliva