Takeda

This study aimed to check the long-term safety and effectiveness of giving a second dose of a cell-based treatment called darvadstrocel to people with Crohn's disease who have complex, hard-to-heal fistulas around the anus. It involved about 53 participants who had already receiv…

This study tested a single injection of a stem cell treatment called darvadstrocel to see if it could help close complex perianal fistulas in children and teenagers with Crohn's disease. Participants first had minor surgery to clean the fistula, then received the injection. Resea…

This study aimed to check the long-term safety of an experimental drug called soticlestat when added to existing seizure medications. It involved 156 children and young adults with severe, hard-to-treat forms of epilepsy, including Dravet and Lennox-Gastaut syndromes. Participant…

This study tested a drug called ponatinib, given with standard chemotherapy, for children and young adults up to age 21 with a specific type of leukemia that had come back or stopped responding to other treatments. The main goals were to find a safe dose and see if the combinatio…

This study tested a new drug called TAK-500, designed to activate the immune system to fight cancer. It was given alone or combined with an existing immunotherapy drug (pembrolizumab) to adults with advanced solid tumors that had stopped responding to standard treatments. The mai…

This early-stage study tested a new drug called TAK-186 in adults with advanced cancers of the head & neck, lung, or colon that could not be removed by surgery. The main goal was to find a safe dose and understand the drug's side effects. Researchers also looked for early signs t…

This study aimed to check the long-term safety of an experimental drug called soticlestat when taken alongside standard medications. It involved about 352 children and adults with Dravet Syndrome or Lennox-Gastaut Syndrome, two rare and severe forms of epilepsy. The main goal was…

This study tested whether a single dose of an experimental drug called danavorexton could help people with moderate to severe sleep apnea breathe more easily in the recovery room after abdominal surgery. The trial involved about 41 participants who were randomly assigned to recei…

This early-stage study aimed to understand how the body absorbs, breaks down, and eliminates an experimental cancer drug called subasumstat in adults with advanced solid tumors. Participants received a single dose containing a tiny, safe amount of radioactive tracer to track the …