Takeda

This study looked at the long-term safety of soticlestat, an add-on seizure medication, in children and adults with Dravet syndrome or Lennox-Gastaut syndrome. Participants took soticlestat along with their usual anti-seizure drugs. The study was terminated early, but the goal wa…

This study looked at whether adding ixazomib to lenalidomide and dexamethasone can help control multiple myeloma in people who already received three cycles of bortezomib-based therapy. About 141 adults took part. The goal was to see how long the disease stayed under control. The…

This study looked at the long-term safety of soticlestat, an add-on seizure medicine, in children and adults with severe epilepsies like Dravet and Lennox-Gastaut syndromes. About 156 participants took the drug twice daily for as long as it helped them. The study was stopped earl…

This study tested a new drug called TAK-186 in adults with advanced head and neck, lung, or colorectal cancer that could not be removed by surgery. The main goals were to check for side effects and find the best dose. The trial was stopped early, but the results help researchers …

This study tested a drug called ponatinib, given with chemotherapy, for children and young adults up to age 21 with a specific type of leukemia (Ph+ ALL) that came back or didn't respond to other treatments. The goal was to find a safe dose and see if the cancer could go into rem…

This study tested a treatment called darvadstrocel for children with Crohn's disease who have complex anal fistulas (abnormal tunnels from the rectum to the skin). Participants first had surgery to clean the fistula, then received an injection of darvadstrocel near the fistula. T…

This study tested a new cell therapy called GDX012 in 16 people with acute myeloid leukemia (AML) that returned or didn't respond to treatment. The main goals were to check safety and find the best dose. The trial was stopped early, so results are limited, but the approach aims t…

This study looked at the long-term safety of giving a second dose of darvadstrocel (a stem cell therapy) to adults with Crohn's disease and complex anal fistulas. 53 participants received one treatment and were monitored for side effects and symptom improvement over several clini…

This study tested a new drug called TAK-500, given alone or with another drug (pembrolizumab), in 61 adults with advanced solid tumors like pancreatic, liver, and lung cancer. The main goals were to check safety and see if the drug could shrink tumors. The study was stopped early…

This study tested a single dose of danavorexton in 41 adults with moderate to severe sleep apnea who were having abdominal surgery. The goal was to see if the drug could help them breathe steadily in the recovery room. The trial was stopped early, and results are not yet availabl…

This study tested a daily medicine called dexlansoprazole to heal and prevent return of esophagus damage in children aged 2 to 11 with erosive esophagitis. The medicine lowers stomach acid to allow the esophagus to heal. The study was stopped early, so results are limited.

This study looked at how the body absorbs, breaks down, and gets rid of the experimental drug subasumstat in adults with advanced solid tumors that had no other treatment options. Only 3 people took part before the study was stopped early. The main goal was to measure the drug an…