Children's heartburn drug trial halted early – but data may still help

NCT ID NCT02615184

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a daily medicine called dexlansoprazole to heal and prevent return of erosive esophagitis (damage to the esophagus from stomach acid) in children aged 2 to 11 years. The trial was stopped early, but researchers aimed to see if the drug could heal the esophagus within 8 weeks and keep it healed for up to 24 weeks. Participants took the medicine or a placebo, and reported symptoms like heartburn and stomach pain.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

esophagitis peptic esophagitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boca Clinical Trials Mexico SC

    Colonia Las Americas, Mexico City, 1120, Mexico

  • Centro Medico Imbanaco de Cali S.A

    Cali, 760042, Colombia

  • Children's Center for Digestive Health Care, LLC

    Atlanta, Georgia, 30342, United States

  • Clinical Research Institute S.C.

    Tlalnepantla, State of Mexico, 54055, Mexico

  • D&H National Research Centers

    Miami, Florida, 33155, United States

  • El Cielo Medical Center

    Puebla City, 72160, Mexico

  • Envision Clinical Research, LLC

    Laredo, Texas, 78041, United States

  • Fundacion Valle del Lili

    Cali, 760032, Colombia

  • GI for Kids

    Knoxville, Tennessee, 37922, United States

  • Gabinet Lekarski Bartosz Korczowski

    Rzeszów, Podkarpackie Voivodeship, 35-302, Poland

  • Gastrointestinal Associates, PA

    Flowood, Mississippi, 39232, United States

  • Hospital Universitario San Ignacio

    Bogotá, 110231, Colombia

  • In Vivo Osrodek Badan Klinicznych

    Bydgoszcz, Kuyavia, 85-048, Poland

  • Inspirepharma S. de R.L. de C.V.

    Monterrey, Nuevo León, 64660, Mexico

  • Instytut "Pomnik - Centrum Zdrowia Dziecka"

    Warsaw, Masovia, 04-730, Poland

  • London Health Sciences Centre (LHSC) - Children's Hospital

    London, Ontario, N6A 5W9, Canada

  • Measurable Outcome Research

    Oklahoma City, Oklahoma, 73112, United States

  • SMIQ S. de R.L. de C.V.

    Querétaro, 76070, Mexico

  • The Children's Hospital of The King's Daughters

    Norfolk, Virginia, 23507, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of California San Francisco

    San Francisco, California, 94158, United States

  • University of South Alabama

    Mobile, Alabama, 36604, United States

  • Uniwersytecki Szpital Dzieciecy w Krakowie

    Krakow, Lesser Poland Voivodeship, 30-663, Poland

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37212, United States

  • Women and Children's Health Research Institute

    Edmonton, Alberta, T6G 1C9, Canada