New GERD drug aims to keep esophagus healed longer

NCT ID NCT07313774

First seen Jan 04, 2026 · Last updated May 15, 2026 · Updated 27 times

Summary

This phase 3 trial tests whether a new drug, linaprazan glurate, can keep the esophagus healed in people with healed erosive esophagitis from GERD, compared to the standard drug lansoprazole. About 1050 adults who were healed in a prior trial will take either high or low dose linaprazan glurate or lansoprazole daily for up to 52 weeks. The study is double-blind and uses endoscopies to check if healing is maintained.

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