New immune therapy tested for Tough-to-Treat cancers

NCT ID NCT04844073

Summary

This early-stage study tested a new drug called TAK-186 in adults with advanced cancers of the head & neck, lung, or colon that could not be removed by surgery. The main goal was to find a safe dose and understand the drug's side effects. Researchers also looked for early signs that the drug could help shrink tumors.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, Seoul Teugbyeolsi, 5505, South Korea

  • Avera Cancer Institute at Sioux Falls

    Heidelberg, Victoria, 3004, Australia

  • Chris O'Brien Lifehouse Hospital

    Sydney, New South Wales, 2050, Australia

  • Columbia University Medical Center -161 Fort Washington

    New York, New York, 10032, United States

  • Fred Hutchinson Cancer Research Center - 1100 Fairview Ave N

    Seattle, Washington, 98109, United States

  • Georgetown University Medical Center

    Washington D.C., District of Columbia, 20007, United States

  • Indiana University

    Indianapolis, Indiana, 43202, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030-4000, United States

  • Mary Crowley Cancer Research Centers Medical City - SCRI - PPDS

    Dallas, Texas, 75230, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Monash University - Australian Centre for Blood Diseases (ACBD)

    Clayton, Victoria, 3168, Australia

  • Northwestern University

    Chicago, Illinois, 60611-2814, United States

  • Novant Health Cancer Institute - Elizabeth Head and Neck

    Charlotte, North Carolina, 28204-3282, United States

  • Paula Fox Melanoma and Cancer Centre

    Melbourne, Victoria, 3004, Australia

  • Samsung Medical Center

    Seoul, 6351, South Korea

  • Sanford Cancer Center

    Sioux Falls, South Dakota, 57105-1521, United States

  • Sarah Cannon Research Institute UK - SCRI - PPDS

    London, Middlesex, W1G 6AD, United Kingdom

  • Scientia Clinical Research Limited

    Randwick, New South Wales, 2031, Australia

  • Seoul National University Hospital

    Seoul, Seoul Teugbyeolsi, 3080, South Korea

  • Severance Hospital Yonsei University Health System

    Seoul, Seodaemun-Gu, 3722, South Korea

  • Southern Oncology Clinical Research

    Bedford Park, South Australia, 5042, Australia

  • The Christie - PPDS

    Manchester, M20 4BX, United Kingdom

  • UC San Diego Moores Cancer Center

    San Diego, California, 92037, United States

  • University of California San Francisco

    San Francisco, California, 94143, United States

  • University of Colorado - Anschutz Medical Campus - PPDS

    Aurora, Colorado, 80045-2517, United States

  • University of Minnesota Medical Center, Fairview

    Minneapolis, Minnesota, 55414-2959, United States

  • Yale University

    New Haven, Connecticut, 06510-3206, United States

Conditions

Explore the condition pages connected to this study.