Experimental cancer drug TAK-186 tested in patients with advanced tumors
NCT ID NCT04844073
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new drug called TAK-186 in 95 adults with advanced or metastatic cancers of the head and neck, lung, or colon that could not be removed by surgery. The main goal was to check for side effects and find the best dose. The study was stopped early, so results are limited.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Asan Medical Center
Seoul, Seoul Teugbyeolsi, 5505, South Korea
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Avera Cancer Institute at Sioux Falls
Heidelberg, Victoria, 3004, Australia
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Chris O'Brien Lifehouse Hospital
Sydney, New South Wales, 2050, Australia
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Columbia University Medical Center -161 Fort Washington
New York, New York, 10032, United States
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Fred Hutchinson Cancer Research Center - 1100 Fairview Ave N
Seattle, Washington, 98109, United States
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Georgetown University Medical Center
Washington D.C., District of Columbia, 20007, United States
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Indiana University
Indianapolis, Indiana, 43202, United States
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MD Anderson Cancer Center
Houston, Texas, 77030-4000, United States
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Mary Crowley Cancer Research Centers Medical City - SCRI - PPDS
Dallas, Texas, 75230, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Monash University - Australian Centre for Blood Diseases (ACBD)
Clayton, Victoria, 3168, Australia
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Northwestern University
Chicago, Illinois, 60611-2814, United States
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Novant Health Cancer Institute - Elizabeth Head and Neck
Charlotte, North Carolina, 28204-3282, United States
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Paula Fox Melanoma and Cancer Centre
Melbourne, Victoria, 3004, Australia
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Samsung Medical Center
Seoul, 6351, South Korea
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Sanford Cancer Center
Sioux Falls, South Dakota, 57105-1521, United States
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Sarah Cannon Research Institute UK - SCRI - PPDS
London, Middlesex, W1G 6AD, United Kingdom
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Scientia Clinical Research Limited
Randwick, New South Wales, 2031, Australia
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Seoul National University Hospital
Seoul, Seoul Teugbyeolsi, 3080, South Korea
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Severance Hospital Yonsei University Health System
Seoul, Seodaemun-Gu, 3722, South Korea
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Southern Oncology Clinical Research
Bedford Park, South Australia, 5042, Australia
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The Christie - PPDS
Manchester, M20 4BX, United Kingdom
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UC San Diego Moores Cancer Center
San Diego, California, 92037, United States
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University of California San Francisco
San Francisco, California, 94143, United States
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University of Colorado - Anschutz Medical Campus - PPDS
Aurora, Colorado, 80045-2517, United States
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University of Minnesota Medical Center, Fairview
Minneapolis, Minnesota, 55414-2959, United States
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Yale University
New Haven, Connecticut, 06510-3206, United States