Sheffield Teaching Hospitals Nhs Foundation Trust

This study tested whether lycopene, an antioxidant found in cooked tomatoes, can improve sperm quality in men with low numbers of swimming sperm. 34 men took either lycopene capsules or placebo for 12 weeks. Researchers compared semen samples before and after to see if lycopene i…

This study looked at whether a very low dose of aspirin (20 mg twice daily) combined with a blood thinner called rivaroxaban (2.5 mg twice daily) works differently than standard treatments in people with chronic coronary syndromes. Forty-eight adults who already take daily aspiri…

This study tested a new MRI technique to see how two common drugs, metformin and ciclosporin, affect the liver's ability to process a special dye. Twelve healthy adults each had two MRI scans, with and without the drugs, to measure changes in liver function. The goal was to valid…

This study looked at how being isolated during the 2020 COVID-19 pandemic affected the mental health of 232 people with inflammatory bowel disease (IBD). Researchers used questionnaires to measure feelings like depression, anxiety, and hopelessness. The goal was to understand wha…

This study tested how different doses of aspirin affect the body's immune response. Healthy volunteers took various aspirin doses for 10-14 days, then received a substance that temporarily mimics flu-like symptoms. Researchers measured immune markers in blood and urine to see if …

This study looked at whether taking a bowel-cleansing solution before a small bowel capsule endoscopy helps doctors see the intestine better and find problems more often. 230 adults referred for the procedure were randomly assigned to receive either a split dose, a single morning…