New MRI technique could spot dangerous drug interactions early

NCT ID NCT07541807

First seen Apr 24, 2026 · Last updated May 15, 2026 · Updated 7 times

Summary

This study tested a new MRI technique to see how two common drugs, metformin and ciclosporin, affect the liver's ability to process a special dye. Twelve healthy adults each had two MRI scans, with and without the drugs, to measure changes in liver function. The goal was to validate this imaging method as a safe tool for detecting drug-drug interactions early in development.

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Contacts and locations

Locations

  • Royal Hallamshire Hospital

    Sheffield, United Kingdom

  • University of Sheffield, POLARIS, 18 Claremont Crescent

    Sheffield, S10 2RX, United Kingdom

Conditions

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