New study aims to sharpen rejection diagnosis in liver transplants

NCT ID NCT03193151

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 32 times

Summary

This study looks at liver transplant biopsy samples to find patterns linked to organ rejection. Researchers will analyze gene activity in 300 biopsies to create a tool that can predict rejection more accurately. The goal is to improve diagnosis, not to test a new treatment. Participants are adults who need a liver biopsy as part of their regular care.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor University Medical Center, Annette C. and Harold C. Simmons Transplant Institute

    COMPLETED

    Dallas, Texas, 75246, United States

  • Centenary Institute of Cancer Medicine & Cell Biology, Royal Prince Alfred Hospital

    COMPLETED

    Camperdown, NSW 2050, Australia

  • Dep. of Nephrology, Transplantation & Internal Med., Samodzielny Publiczny Szpital Kliniczny im. A. Mieleckiego

    COMPLETED

    Katowice, 40-027, Poland

  • Division of Transplant Surgery, University of Washington

    COMPLETED

    Seattle, Washington, 98195, United States

  • Henry Ford Transplant Institute

    RECRUITING

    Detroit, Michigan, 48202, United States

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • Independent Public Composite Regional Hospital

    COMPLETED

    Szczecin, 71-455, Poland

  • Institute for Liver Science, King's College London

    COMPLETED

    London, SE5 9NU, United Kingdom

  • Northwestern Memorial Hospital

    COMPLETED

    Chicago, Illinois, 60611, United States

  • Transplant Surgery, VCU Medical Center

    COMPLETED

    Richmond, Virginia, 23298, United States

  • University of Alberta, Laboratory Medicine and Pathology

    COMPLETED

    Edmonton, Alberta, T6G 2R7, Canada

  • University of California San Francisco, Transplant Research Unit

    COMPLETED

    San Francisco, California, 94143, United States

  • University of Maryland School of Medicine

    COMPLETED

    Baltimore, Maryland, 21201, United States

  • Vanderbilt University Medical Center, Vanderbilt Transplant Center

    WITHDRAWN

    Nashville, Tennessee, 37232, United States

  • Warsaw Medical University, Independent Public Clinical Hospital

    COMPLETED

    Warsaw, 02-097, Poland

  • Warsaw Medical University, Jesus the Child Clinical Hospital

    COMPLETED

    Warsaw, 02-005, Poland

Conditions

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