Could a tiny aspirin dose plus a blood thinner be safer for heart patients?

NCT ID NCT04990791

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a new combination of very low-dose aspirin (20 mg twice daily) plus a blood thinner called rivaroxaban (2.5 mg twice daily) in 48 adults with chronic coronary syndromes. Researchers compared this new regimen to standard aspirin alone (75 mg once daily) and standard aspirin plus rivaroxaban. They measured bleeding time, blood clotting, and inflammation markers to see if the new combo might be safer and just as effective. The goal was to gather information, not to treat or cure the disease.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome intermediate coronary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sheffield Teaching Hospitals NHS Foundation Trust

    Sheffield, South Yorkshire, S5 7AU, United Kingdom