Shanghai 10th People's Hospital

This early-stage trial tests a drug called romiplostim in 280 sepsis patients with very low platelet counts (under 50). The drug is given as a weekly shot to try to raise platelet levels. Researchers will compare it to a standard treatment and check how well it works after 7 days…

This study looks at whether the drug guselkumab can stop Crohn's disease from coming back after bowel surgery. About 88 adults with moderate to severe Crohn's who have had surgery will receive guselkumab and be monitored for up to 48 weeks. The main goal is to see if the disease …

This study tests whether adding fecal microbiota transplantation (FMT) – transferring gut bacteria from a healthy donor – to standard chemotherapy can shrink tumors in people with advanced colorectal cancer that cannot be removed by surgery. About 220 adults will be randomly assi…

This study tests a procedure called renal denervation, which uses energy to calm overactive nerves in the kidneys, to see if it can safely lower diastolic blood pressure (the bottom number) in people with isolated diastolic hypertension. About 124 adults who have never taken bloo…

This study tests whether Coenzyme I injections can reverse vascular aging in 60 adults aged 40-70 with stiff arteries. Participants receive either the coenzyme or a placebo, and researchers measure changes in blood vessel function and stiffness over 28 days. The goal is to see if…

This early study will test a new type of immune cell therapy in 20 people with advanced bladder cancer that hasn't responded to standard treatments. The therapy uses the patient's own γδ-T cells, which are grown in a lab and then infused back to attack the cancer. The main goal i…

This study will test a new rapid test called NuRapid-CRISPR that uses CRISPR technology to quickly find the germ causing sepsis in ICU patients. The goal is to see if using this test helps doctors choose the right antibiotics faster and reduces deaths within 28 days. About 396 ad…

This trial tests whether short peptide enteral nutrition formulas help ICU patients with a high risk of pancreatic exocrine insufficiency absorb protein better than standard whole protein formulas. Researchers will measure amino acid levels and other markers in 250 critically ill…