Second Xiangya Hospital Of Central South University

This study aims to see if closing a small, common heart hole called a patent foramen ovale (PFO) can improve brain function and reduce severe migraines in adults. Researchers will follow 45 adults with frequent migraines and a PFO who are already scheduled for the closure procedu…

This study is testing whether adding a new, long-acting drug called cofrogliptin to standard care can help preserve the body's ability to make insulin in adults with LADA, a slow-onset form of autoimmune diabetes. Over 52 weeks, 84 participants will take either standard therapy p…

This study is testing if a non-invasive brain stimulation technique (rTMS) can improve 'cognitive flexibility'—the ability to switch between thoughts and tasks—in people with major depression. Researchers believe a specific weak connection in the brain causes this thinking proble…

This study is testing if sorafenib, a drug used for some cancers, can help preserve the body's own insulin production in adults recently diagnosed with type 1 diabetes. It will involve 10 participants who will take either the drug or a placebo for 26 weeks. The main goal is to se…

This study is testing an online therapy and education program designed to help parents of children with hearing loss who have received cochlear implants. The program aims to reduce parental stress, anxiety, and depression while improving parenting skills. Researchers will compare…

This study aims to create a computer model that can predict which patients with a severe facial pain condition (trigeminal neuralgia) are most likely to have their pain return after a specific surgical procedure. Researchers will look back at the medical records, scans, and surge…

This study aims to find a better way to predict a dangerous drop in blood pressure when elderly patients are put under general anesthesia. Researchers will observe 86 patients aged 65 and older during elective surgery. They will measure changes in blood pressure while patients ta…