Could a broccoli compound help schizophrenia symptoms?

NCT ID NCT07652866

Not yet recruiting Symptom relief Sponsor: Second Xiangya Hospital of Central South University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a daily supplement of sulforaphane, a compound found in broccoli sprouts, can improve negative symptoms (like lack of motivation) and thinking problems in people with schizophrenia. Sixty participants aged 12 to 45 who are stable on antipsychotic medication will receive either sulforaphane or a placebo for 12 weeks, followed by an optional 12-week open-label phase. The study will measure changes in symptom scales and brain imaging.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sulforaphane (a compound found in broccoli sprouts)
What this could lead to: If it works, this could point toward a new way to help with hard-to-treat symptoms like lack of motivation and trouble thinking clearly in schizophrenia.
What could go wrong: This is a small, early-stage trial with only 60 people. The supplement may not work better than a placebo, and results may not apply to everyone with schizophrenia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SCHIZOPHRENIA DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SCHIZOPHRENIA DISORDER

Contacts and locations

Locations

Xiangya Second Hospital

Changsha, China, 410001, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.