Heart hole closure may rewire migraine brains, new study hints

NCT ID NCT07343154

First seen Jan 16, 2026 · Last updated May 15, 2026 · Updated 21 times

Summary

This study looks at 45 adults with migraine with aura and a small hole in the heart called PFO. It aims to see if closing that hole can improve brain activity, thinking, and mood over 12 months. Participants will have brain scans, memory tests, and fill out questionnaires before and after the procedure.

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