Roswell Park Cancer Institute

This is a first-in-human study to test the safety and find the right dose of a new cell therapy called GB-5267 for women with ovarian cancer that has stopped responding to platinum chemotherapy. The therapy involves taking a patient's own immune cells (T-cells), engineering them …

This study is testing whether combining a light-activated drug with immunotherapy can help control advanced non-small cell lung cancer that hasn't responded to standard treatments. The treatment involves injecting a drug that becomes active when exposed to a special laser light, …

This early-stage trial is testing a new oral drug called GB1211 (selvigaltin) in combination with standard treatments for multiple myeloma that has come back or stopped responding to previous therapies. The main goals are to find the safest dose and understand the side effects wh…

This study is testing whether a new type of ultrasound, placed on the skin between the scrotum and anus, can create clearer pictures of the prostate to help doctors find cancer during a biopsy. Researchers will compare this new skin-surface method to the standard internal ultraso…

This study is testing whether a low dose of psilocybin, the active compound in 'magic mushrooms,' combined with talk therapy, can help reduce chronic pain in cancer patients who rely on opioid painkillers. It will involve 20 adult patients with active cancer and moderate-to-sever…

This study aims to understand how using nicotine vapes before or after THC vaping affects how much THC enters the bloodstream and how people feel. Researchers will enroll 60 adults who regularly use both THC and nicotine vaping products. Participants will complete several control…

This study aims to understand how the body processes THC differently when it comes from vaping liquids versus traditional smoked cannabis. Researchers will measure THC levels in the blood and short-term effects in 40 healthy adults who already use both products. The goal is to ga…