New Vaccine-Drug combo aims to fight tough lung cancer

NCT ID NCT07543172

First seen Apr 28, 2026 · Last updated Apr 28, 2026

Summary

This study tests a combination of a cancer vaccine (CIMAVAX-EGF) and targeted drugs (sotorasib or adagrasib) in about 29 adults with advanced non-small cell lung cancer that has a specific KRAS G12C mutation. The vaccine helps the immune system attack cancer cells, while the drugs block signals that make cancer grow. The goal is to see if this combo can keep the cancer from getting worse for longer.

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Contacts and locations

Locations

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

Explore the condition pages connected to this study.