Peking Union Medical College Hospital

This Phase 2 trial is testing a combination of paclitaxel polymer micelle and immunotherapy for people with advanced biliary tract cancer whose disease has progressed after standard first-line treatment. The study aims to see if this new drug combo can shrink tumors and control t…

This phase 2 trial is testing whether combining daratumumab, venetoclax, and dexamethasone can produce a deep and rapid response in people newly diagnosed with light-chain (AL) amyloidosis who carry a specific genetic marker called t(11;14). The study enrolls 36 participants and …

This phase 2 trial tests whether adding plinabulin to a standard combination of pembrolizumab and docetaxel can shrink tumors or slow disease progression in people with metastatic non-small cell lung cancer that has worsened after prior immunotherapy. About 47 adults with advance…

This trial tests whether giving the immunotherapy drug camrelizumab before surgery can help completely remove T4 colon cancers that have a specific genetic feature (dMMR). These cancers often don't respond well to standard chemotherapy. The study will enroll 18 adults who will re…

This trial tests a combination of two drugs, sirolimus and all-trans retinoic acid (ATRA), for people with autoimmune anemia that has not responded to standard treatments. Autoimmune anemia occurs when the immune system attacks red blood cells, causing fatigue and other symptoms.…

This study tests whether adding an immunotherapy drug (tislelizumab) to standard chemoradiation before surgery can improve outcomes for people with locally advanced rectal cancer. About 100 participants will receive the combination treatment, and researchers will measure how many…

This trial tests whether combining roxadustat with retinoic acid can help people with low-risk myelodysplastic syndromes (MDS) whose disease hasn't responded to initial treatment. The goal is to improve blood cell counts and reduce the need for transfusions. Participants will tak…

This study tests online adaptive radiotherapy, a type of radiation that adjusts in real-time to target cervical cancer more precisely. By using smaller treatment margins, doctors hope to reduce side effects while still effectively treating the tumor. The trial involves 30 adults …

This study planned to test the drug hetrombopag in people with non-severe aplastic anemia, a condition where the bone marrow doesn't make enough blood cells. The goal was to see if the drug could safely raise platelet counts. However, the trial was withdrawn before enrolling any …

This study was designed to test whether combining cyclosporine with drugs that boost platelet production (eltrombopag, hetrombopag, or romiplostim) could help people with newly diagnosed severe aplastic anemia who need blood transfusions. The trial was withdrawn before enrolling …

This trial aimed to compare the safety and effectiveness of adding luspatercept to cyclosporine versus cyclosporine alone in adults newly diagnosed with non-severe aplastic anemia (NSAA). The goal was to see if the combination could improve blood cell counts better than the stand…

This study was designed to test whether romiplostim N01 could help people with aplastic anemia caused by chemotherapy or radiation therapy. The trial was withdrawn before enrolling any participants, so no results are available. It was planned as a small, early-stage study at a si…

This study was designed to test whether adding enarodustat to cyclosporine helps people with a type of aplastic anemia who need regular blood transfusions. The trial was withdrawn before enrolling any participants, so no results are available. It would have compared the combinati…

This study tests a special device that combines a vaginal dilator with a drug delivery tube to help prevent vaginal narrowing and scarring after pelvic radiation therapy. About 76 women aged 18-70 who have completed radiation for pelvic tumors will use the device regularly. The g…

This early-phase trial tests a new drug called RAG-18 in 12 boys aged 4-15 with Duchenne muscular dystrophy. The drug is a small activating RNA given through an IV, designed to help muscles work better. The main goal is to check safety and how the body handles the drug, with earl…

This early-stage study tests a new drug called NYM096 in people with advanced clear cell kidney cancer that has spread. The study has two parts: first, using a low dose to see if it can light up tumors on scans, and second, giving higher doses to see if it can shrink tumors and f…

This study tests a new, less invasive treatment for large thyroid nodules (giant nodular goiter) that cause discomfort or breathing problems. The procedure uses a tiny tube to deliver a chemotherapy drug (bleomycin) directly into the nodule's blood supply, blocking it and shrinki…

This study compares a robotic system to traditional manual methods for performing cerebral angiography, a procedure that images blood vessels in the brain. Researchers will enroll 450 patients aged 18-75 with suspected head or neck vascular issues. The goal is to see if the robot…

This study compares two endoscopic procedures—EUS-BD and ERCP-BD—for draining blocked bile ducts caused by cancers near the pancreas or bile duct. Forty adults with distal malignant bile duct obstruction will be randomly assigned to one of the two procedures. The main goal is to …

This early-phase study tests a new radioactive tracer called [68Ga]Ga-NOTA-RF for PET scans in 30 people with pituitary tumors. The goal is to see if this tracer can better highlight tumors and help doctors tell different tumor types apart. Participants receive an injection of th…

This study tests a newer type of radiation therapy called online adaptive radiotherapy (oART) for people who have had surgery for endometrial or cervical cancer. The goal is to see if using smaller treatment margins can reduce side effects while still effectively targeting any re…

This pilot study tests whether taking ondansetron, a common anti-nausea drug, before an unsedated throat scope (EGD) can reduce gagging, nausea, and overall discomfort. About 40 Chinese patients who have had this exam before will either receive ondansetron plus a numbing gargle, …

This observational study looks at how common adverse events (medical errors or complications) are among hospitalized adults in China and compares four different ways to detect them. Researchers review medical records from five hospitals to identify events, assess their severity a…

This study tests whether an AI training agent can improve medical students' clinical reasoning skills compared to traditional study materials. About 88 students from two Chinese medical schools will be randomly assigned to use either the AI tool or standard case materials. Resear…

This study explores whether 3D bioprinting can create personalized models of liver cancer from a patient's own tumor tissue. Researchers will test different drugs on these models to see which ones work best, aiming to predict a patient's response before treatment. The goal is to …

This study follows 1000 adults who have had a stroke to better understand how the brain recovers. Researchers use brain scans, electrical signals, and physical tests to find patterns linked to recovery. The goal is to improve predictions and treatments for stroke survivors.

This study follows 60 people with cervical adenocarcinoma to see how their tumors respond to radiotherapy. Researchers will use imaging and tissue samples to better predict outcomes and guide next steps, like surgery or additional treatment. The goal is to improve monitoring and …

This study surveys 3,000 women aged 40 and older in Chinese communities to understand how aware they are of breast self-exams and how often they do them. Using a health belief model, researchers will look at what factors influence these practices. The goal is to find gaps between…