Mahidol University

This study tests whether aminophylline, a medicine usually used for asthma, can help prevent kidney damage in children receiving cisplatin chemotherapy. About 24 children under 18 will receive either aminophylline or a placebo alongside their standard hydration. Researchers will …

This study tests whether giving extra human albumin (a natural blood protein) to patients with septic shock after surgery can improve their chances of survival. Septic shock is a life-threatening condition where infection causes dangerously low blood pressure. The trial will invo…

This study compares the Invisalign Palatal Expander (IPE) with the Rapid Palatal Expander (RPE) in children aged 8–12 who have a narrow upper jaw and an underbite (skeletal Class III). Participants will wear a facemask after expansion. Researchers use 3D X-rays to measure changes…

This study tests whether adding stem cells from donated placentas to standard cooling therapy can improve outcomes for newborns with brain injury caused by lack of oxygen at birth. About 40 infants with moderate to severe injury will receive either stem cells or a placebo within …

This study compares using one antibiotic (beta-lactam) alone versus combining it with another (levofloxacin) to treat strep bloodstream infections. About 165 adults with strep in their blood will be randomly assigned to one of the two treatments. The goal is to see if the single …

This study tests whether a computer-based stepping game, called Smart±step, can help older adults with mild cognitive impairment (MCI) improve their balance, thinking, and quality of life while reducing their risk of falling. About 70 participants will use the game, which combine…

This study compares two treatments—high-intensity laser therapy and focused shock wave therapy—for people with plantar fasciitis, a common cause of heel pain. About 28 adults will receive one of the treatments plus exercises, and researchers will track pain and foot function for …

This study tests whether a nerve block injection can help people with migraine who overuse painkillers. About 130 adults will receive either the nerve block or a placebo. The goal is to see if the injection reduces headache days and helps them stop relying on painkillers.

This study tests a new care program for older adults in Thailand who have had a heart attack. The program combines in-person education, motivational counseling, and a mobile app to help them adopt healthy habits and track their recovery. Researchers will measure if this approach …

This study tests whether a 14-day course of the antibiotic rifaximin can reduce bothersome bloating in adults with irritable bowel syndrome, functional constipation, or similar gut disorders. About 78 participants will receive either rifaximin or a placebo, and researchers will m…

This study tests whether a sleep medication called lemborexant can help older adults in the intensive care unit (ICU) sleep better and reduce their risk of delirium, a state of sudden confusion. The trial will involve 100 patients aged 65 and older who are in the surgical ICU. Pa…

This study looks at how the amount of deep sleep just before waking up affects how alert people feel after a 2-hour nap at night. Researchers will monitor brain activity and test reaction times in 28 healthy adults. The goal is to understand sleep inertia, which could help improv…

This study tests whether a simple brain activity monitor (BIS) can predict how well critically ill patients with decreased consciousness will do. Researchers will compare BIS readings from 40 ICU patients—half with very low consciousness and half more alert—and track their hospit…

This study is creating a new questionnaire to measure how well children recover after anesthesia and surgery. Researchers will work with 200 children aged 2-17 and their parents to develop and test the tool. The goal is to provide a simple, child-friendly way to assess recovery q…

This study looks at how mild electrical brain stimulation (tDCS or tACS) combined with physical therapy affects brain activity in stroke survivors. 60 adults who had a stroke 2 weeks to 5 years ago will take part. The goal is to measure changes in blood oxygen levels in the brain…

This study watches how the heart responds to two common treatments for septic shock: intravenous fluids and blood-pressure-raising medications (vasopressors). Researchers will use echocardiograms (heart ultrasounds) before and after treatment in 180 adults. The goal is to see whi…