London Health Sciences Centre Research Institute Or Lawson Research Institute Of St. Joseph's

This study is testing a new, small wearable device designed to gently remove extra fluid from dialysis patients between their regular hospital treatments. The goal is to reduce the dangerous strain that rapid fluid removal during dialysis puts on the heart and other organs, which…

This study aims to verify if the current gentamicin dosing schedule used for newborns (up to 7 days old) with a serious blood infection (sepsis) is still safe and effective. Researchers will measure antibiotic levels in the babies' blood and check for any signs of kidney or heari…

This study aims to make diagnosing Alzheimer's disease faster and more accessible. It will test a nurse-led screening tool to identify eligible patients for new blood tests and brain scans, bypassing long waits for specialist appointments. The goal is to reduce the time to diagno…

This study is testing if a special therapy program can help reduce anxiety in children who have both autism and an intellectual disability. The program, called Facing Your Fears, teaches kids and their parents strategies to manage worries. Researchers will work with about 24 chil…

This study is testing whether smart glasses powered by artificial intelligence can help people with significant, permanent vision loss move around more safely and independently. Fifty participants with conditions like glaucoma or retinal dystrophy will be split into two groups: o…

This early-stage study is testing whether taking an oral L-Carnitine supplement can help people with heart failure feel better. Researchers want to see if this naturally occurring substance, which helps the body turn fat into energy, can improve symptoms, heart function, and qual…

This study is testing a special numbing injection, given during surgery, to see if it can effectively manage pain for children after tonsil removal. The goal is to reduce or eliminate the need for opioid painkillers, which can have side effects, especially in kids with sleep apne…

This study is testing whether a meditation program or a general health education program can improve quality of life and mental health for older adults who have permanent, age-related vision loss and for the people who care for them. Researchers will enroll 150 participants to tr…

This study is testing whether a body-focused therapy called SMART can help adults with Post-Traumatic Stress Disorder (PTSD). SMART uses movement, touch, and balance exercises to help people feel more connected to their bodies and surroundings. Researchers will enroll 80 adults t…

This study aims to understand if differences in gut bacteria are linked to why some knee replacements fail and require repeat surgery. Researchers will compare gut bacteria samples from 30 people with successful knee replacements to those needing revision surgery. The goal is to …

This study aims to better understand how a drug called desmopressin, which is often given to control bleeding, affects the blood's ability to clot during and after major heart surgery. Researchers will enroll 100 patients and use a special blood test (TEG6) to measure changes in …

This study aims to understand why some people develop chronic pain lasting more than 3 months after chest surgery. Researchers will follow 60 patients having chest surgery, checking their pain levels and analyzing blood samples before and after the operation. They are looking for…

This study aims to see if standard fasting rules before surgery work the same for people with epilepsy. Researchers suspect epilepsy or its medications might slow digestion, leaving food or liquid in the stomach, which could be risky during anesthesia. They will use a quick, pain…

This study aims to see if a simple, non-invasive eye ultrasound can help predict which patients become confused after heart surgery. Researchers will measure the thickness of a nerve behind the eye in 300 patients before and after their operation. They will compare these measurem…