Could a lung scarring drug ease rare windpipe narrowing?
NCT ID NCT07654517
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if pirfenidone, a drug used for lung scarring, can safely slow scar buildup in the windpipe of people with idiopathic subglottic stenosis (iSGS). About 40 adults will receive either pirfenidone or a placebo for one year, alongside their usual steroid injections. The main goal is to check safety and tolerability, while also looking for signs that the drug may delay the need for airway dilation procedures.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Schulich School of Medicine and Dentistry
London, Ontario, N6A 4L6, Canada
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