Which diuretic protects a new kidney best? a Head-to-Head trial puts furosemide and mannitol to the test
NCT ID NCT07726134
First seen Jul 24, 2026 · Last updated Jul 24, 2026
Summary
This trial compares two common diuretics—furosemide and mannitol—given during kidney transplant surgery to see which better prevents delayed graft function, a condition where the new kidney does not work right away and requires dialysis. The study enrolls adults receiving a deceased-donor kidney transplant. It aims to gather feasibility data and early signals on which drug may reduce complications and improve recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- furosemide or mannitol given intravenously during kidney transplant surgery
- What this could lead to
- If one drug proves better, it could reduce the need for dialysis after kidney transplant and improve long-term graft survival.
- What could go wrong
- This is a small pilot study focused on feasibility, not definitive results. The two drugs may turn out to be equally effective, or neither may show a clear advantage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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London Health Sciences Centre
London, Ontario, n6a 5a5, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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