Leiden University Medical Center

This study tested a virtual coach designed to help adults quit smoking and become more physically active. About 100 participants used the coach for around 16 weeks. The goal was to see if the program was easy to use and liked by users, not to prove it works for everyone.

This study tested a new way of clamping the umbilical cord in very preterm babies (born before 30 weeks). Instead of clamping at a set time, doctors waited until the baby was stable—breathing well with good heart rate and oxygen levels—before clamping. The goal was to see if this…

This study tested a decision rule that combines a checklist (Marburg Heart Score) with a rapid blood test (high-sensitive troponin I) to help general practitioners decide if patients with new chest pain need hospital referral. About 946 adults with acute chest pain took part. The…

This study tested whether a simple checklist called the YEARS algorithm could safely reduce the number of CT scans needed to diagnose blood clots in the lungs of people with active cancer. About 700 adults with cancer and suspected clots were randomly assigned to either the YEARS…

This study tested a nurse-led education program to help people with serious illness or frailty manage dry mouth. 70 participants either received the program or usual care. The goal was to see if the program could reduce dry mouth severity by at least 2 points on a 0-10 scale afte…

This study looked at whether teaching primary care doctors better ways to treat insomnia can help their patients sleep better. About 485 patients with insomnia symptoms completed surveys. Researchers compared patients whose doctors received special training with those getting usu…

This study looked at whether breast and prostate cancer patients can safely take a lower dose of the steroid dexamethasone before their chemo drug docetaxel. The standard high dose can cause side effects like high blood sugar, mood changes, and weakened immunity. Researchers test…

This study looked at over 1,000 preterm infants with very low platelet counts to create a tool that predicts their risk of major bleeding or death. The goal is to help doctors decide whether a platelet transfusion would help or harm each baby at a given moment. The model uses the…