New model helps doctors decide when to give platelet transfusions to preterm babies

NCT ID NCT06043050

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 29 times

Summary

This study looked at over 1,000 preterm infants with very low platelet counts to create a tool that predicts their risk of major bleeding or death. The goal is to help doctors decide whether a platelet transfusion would help or harm each baby at a given moment. The model uses the baby's current health information to give personalized risk estimates, aiming to improve care in the neonatal intensive care unit.

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Contacts and locations

Locations

  • Amsterdam University Medical Center, Emma Children's hospital, location AMC

    Amsterdam, North Holland, 1105 AZ, Netherlands

  • Amsterdam University Medical Center, Emma Children's hospital, location VUmc

    Amsterdam, North Holland, 1081 HV, Netherlands

  • Charité - Universitätsmedizin Berlin

    Berlin, Metropolregion Berlin-Brandenburg, 10117, Germany

  • Erasmus University Medical Center, Sophia pediatric hospital

    Rotterdam, South Holland, 3015 CN, Netherlands

  • Isala clinics

    Zwolle, Overijssel, 8025 AB, Netherlands

  • Karolinska University Hospital

    Stockholm, Södermanland and Uppland, 171 76, Sweden

  • Leiden University Medical Center, Willem Alexander Children's hospital

    Leiden, South Holland, 2333 ZA, Netherlands

  • Maastricht University Medical Center, MosaKids

    Maastricht, Limburg, 6229 HX, Netherlands

  • Máxima Medical Center

    Veldhoven, North Brabant, 5504 DB, Netherlands

  • Radboud University Medical Center, Amalia Children's hospital

    Nijmegen, Gelderland, 6525 GA, Netherlands

  • University Medical Center Groningen, Beatrix Children's hospital

    Groningen, Provincie Groningen, 9713 GZ, Netherlands

  • University Medical Center Utrecht, Wilhelmina Children's hospital

    Utrecht, Utrecht, 3584 EA, Netherlands

Conditions

Explore the condition pages connected to this study.