Johns Hopkins University

This phase 3 trial tests whether an oral antioxidant called N-acetylcysteine (NAC) can slow the loss of vision in people with retinitis pigmentosa, an inherited eye disease that causes night blindness and tunnel vision. About 485 adults aged 18 to 65 will take NAC or a placebo da…

This study tests an experimental treatment for pregnant women whose babies have no amniotic fluid because of severe kidney problems. The treatment involves repeatedly adding sterile fluid into the womb to help the baby's lungs grow enough to survive after birth. The study include…

This early study tests whether giving a newborn a small dose of their parent's healthy nasal bacteria can help prevent staph infections. The trial involves 34 infants in the NICU and their parents. Researchers will check if the baby's nose bacteria become more diverse and resista…

This study looks at whether psilocybin, the active ingredient in magic mushrooms, can help people who have both major depression and alcohol use disorder. About 90 adults will receive psilocybin in a controlled setting to see if it reduces depressive symptoms and heavy drinking. …

This study tests whether low-dose ketamine infusions can reduce fatigue in people with multiple sclerosis (MS). About 110 adults with MS and significant fatigue will receive either ketamine or a placebo. The goal is to see if ketamine can safely improve fatigue symptoms.

This study tests if an injection of hyaluronidase can help reduce muscle stiffness in the arm after a stroke. About 56 people with moderate to severe arm stiffness will receive either the study drug or a placebo, and later switch to the other option. The goal is to see if the tre…

This study was designed to see if a new ultrasound device with a needle guide could help doctors place needles into the femoral artery more safely during a liver cancer treatment called chemoembolization. The study was withdrawn before any participants were enrolled, so no result…

This study was designed to test if tartrazine, a common yellow food dye, could be rubbed on the skin to make it temporarily transparent. Researchers planned to apply different doses to healthy volunteers and take pictures to see if they could better see blood vessels and other st…

This study aims to find new antibodies in the blood that might be causing certain stomach and bowel movement disorders. Researchers will analyze blood samples from 300 people over age 13 who have ongoing gut symptoms. The goal is to better understand if the immune system is attac…