Magic mushroom compound targets depression and drinking together

NCT ID NCT04620759

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 25 times

Summary

This study looks at whether psilocybin, the active ingredient in magic mushrooms, can help people who have both major depression and alcohol use disorder. About 90 adults will receive psilocybin in a controlled setting to see if it reduces depressive symptoms and heavy drinking. The goal is to improve mood and cut down on alcohol use.

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Contacts and locations

Locations

  • Johns Hopkins Center for Psychedelic and Consciousness Research

    Baltimore, Maryland, 21224, United States

Conditions

Explore the condition pages connected to this study.