New injection aims to ease stroke-related muscle stiffness

NCT ID NCT03306615

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests whether an injection of hyaluronidase can reduce muscle stiffness and spasticity in the arm after a stroke. 56 adults with moderate-to-severe stiffness will receive either the study drug or a placebo, and later switch to the other option. The goal is to improve range of motion and arm function.

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Conditions

The condition(s) this trial relates to.

cerebral palsy hyperreflexia Muscle Spasticity stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Johns Hopkins School of Medicine

    Baltimore, Maryland, 21231, United States