Johns Hopkins University
Clinical trials sponsored by Johns Hopkins University, explained in plain language.
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Quick HCV treatment with peer help boosts cure rates in drug users
Disease control CompletedThis study tested two ways to give hepatitis C treatment to people who use drugs and are in an opioid treatment program. One group got fast treatment with a peer mentor who had been cured of HCV, while the other group was sent to a regular clinic. The goal was to see which approa…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Apr 29, 2026 02:42 UTC
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Virtual counselor aims to help smokers quit in small pilot study
Disease control CompletedThis study tested a computer program called C-Raven that uses a virtual counselor to help people stop smoking. 18 adults who smoked daily took part. The program included two 20-minute iPad sessions and optional nicotine replacement therapy, plus follow-up support from a community…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Apr 29, 2026 02:39 UTC
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Can a heart drug fix tiny vessel damage in metabolic syndrome?
Disease control CompletedThis study tested whether vericiguat, a drug that helps blood vessels relax, could improve heart artery function in 45 adults with metabolic syndrome (a cluster of conditions like high blood pressure, large waist, and abnormal cholesterol). Participants took either vericiguat or …
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Apr 29, 2026 02:38 UTC
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Quick HIV tests could stop spread by getting people treated same day
Diagnosis CompletedThis study looked at new rapid HIV tests that give results during a single clinic visit. The goal was to see if these quick tests help more people start HIV treatment or prevention medicine right away. 224 adults at high risk for HIV in Baltimore took part. The results could help…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Apr 29, 2026 02:39 UTC
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Can a phone coach help Moms-to-Be avoid excess weight and diabetes?
Prevention CompletedThis study tested a program called Healthy for Two/Healthy for You, where health coaches called pregnant women to help them manage weight gain. The goal was to prevent too much weight gain during pregnancy, lower the risk of gestational diabetes, and reduce long-term obesity in b…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Prevention
Last updated Apr 29, 2026 02:38 UTC
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Drumming away symptoms: Beat-Based therapy shows promise for Parkinson's and Huntington's
Symptom relief CompletedThis study looked at whether group drum classes, held twice a week for 12 weeks, could help people with Parkinson's or Huntington's disease feel better and move more easily. 18 adults aged 18-89 took part, along with a study partner. Researchers measured changes in anxiety, depre…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 29, 2026 02:39 UTC
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New therapy aims to lift depression and boost mobility after ICU stays
Symptom relief CompletedThis study tested a program that combines depression treatment with physical rehabilitation for people who survived acute respiratory failure in the ICU. The therapy was delivered by phone and home visits. The goal was to see if this approach is practical and might improve both m…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 29, 2026 02:38 UTC
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New program aims to help HIV patients kick the habit
Symptom relief CompletedThis study tested a program to help hospitalized people with HIV quit smoking. It used two computer sessions and a community health worker for support. The goal was to see if the program was practical and liked by patients, and if it helped them feel ready to quit. 22 adults took…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 29, 2026 02:38 UTC
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Sleep therapy may boost recovery success for substance use patients
Symptom relief CompletedThis study looked at whether a short sleep program (Brief Behavioral Therapy for Insomnia) helps people living in a residential substance use treatment center sleep better and stay in recovery longer. About 83 adults took part, wearing sleep trackers and completing surveys. Resea…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 29, 2026 02:38 UTC
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Simple home help and exercises may keep seniors independent after hospitalization
Symptom relief CompletedThis study tested a program called CAPABLE in 268 older adults who had recently been in the hospital. The program included help with medications, strength and balance exercises, pain management, and home modifications. The goal was to see if these services could improve their abi…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 29, 2026 02:37 UTC
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New tool helps doctors spot and solve Patients' hidden social problems
Knowledge-focused CompletedThis study tested a computer tool that helps doctors identify social needs—like trouble getting food or housing—in African American patients with chronic diseases such as diabetes or high blood pressure. The tool gave patients a risk score and suggested referrals to community org…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:40 UTC
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Scientists probe why scleroderma and lung hypertension weaken the heart
Knowledge-focused CompletedThis study looked at 43 people with scleroderma or unexplained pulmonary arterial hypertension (PAH) to understand why their right heart weakens. Researchers collected blood and tissue samples during routine procedures and measured heart function over six months. The goal was to …
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:39 UTC
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Scientists measure hidden lung pressures to predict treatment needs
Knowledge-focused CompletedThis study measured the pressure inside the chest of 37 adults with a collapsed lung (pneumothorax) during standard treatment. The goal was to see if these pressure readings could help doctors understand which patients might need more advanced procedures. The research did not tes…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:37 UTC