Scientists probe why scleroderma and lung hypertension weaken the heart

NCT ID NCT04610788

First seen Jan 10, 2026 · Last updated Apr 28, 2026 · Updated 16 times

Summary

This study looked at 43 people with scleroderma or unexplained pulmonary arterial hypertension (PAH) to understand why their right heart weakens. Researchers collected blood and tissue samples during routine procedures and measured heart function over six months. The goal was to learn how standard PAH treatments affect the right ventricle, not to test a new therapy.

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Contacts and locations

Locations

  • Johns Hopkins

    Baltimore, Maryland, 21287, United States

Conditions

Explore the condition pages connected to this study.