Johns Hopkins University
Clinical trials sponsored by Johns Hopkins University, explained in plain language.
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Grocery delivery and coaching tested to lower blood pressure
Disease control CompletedThis study tested whether a digital program that includes grocery delivery and health coaching could help adults with high blood pressure and limited food access eat a heart-healthy diet. 67 participants received an Instacart+ membership, weekly grocery lists, and coaching via te…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Apr 26, 2026 20:02 UTC
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Heart attack drug shows promise in lowering cholesterol and inflammation
Disease control CompletedThis study tested whether evolocumab, a drug that lowers LDL cholesterol, can also reduce inflammation in the heart and blood vessels after a heart attack. Sixty adults with a certain type of heart attack (NSTEMI) received either evolocumab or a placebo. The main goals were to se…
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Apr 26, 2026 20:02 UTC
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New program helps kids with emotional challenges achieve healthier weight
Disease control CompletedThis study tested a 12-month healthy weight program for 112 youth aged 8-18 with serious emotional disturbance who were overweight or obese. Participants worked with a health coach on diet, activity, and weight management, involving both the child and parents. The goal was to red…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Apr 26, 2026 20:00 UTC
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Which drug keeps COPD patients out of the hospital? a Head-to-Head trial
Prevention CompletedThis study tested two medications, roflumilast and azithromycin, to see which one works better at preventing hospitalizations or death in people with severe COPD and chronic bronchitis. Over 1,000 participants were followed for up to 72 months. The goal was to find the most effec…
Phase: PHASE4 • Sponsor: Johns Hopkins University • Aim: Prevention
Last updated Apr 26, 2026 20:02 UTC
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Nurse-Led PrEP program boosts HIV prevention in Women's clinics
Prevention CompletedThis study looked at whether a specially trained nurse could help more women at risk for HIV learn about and start taking PrEP, a daily pill that prevents HIV. The study involved 440 women receiving care in OB/GYN clinics. Half got standard care plus the nurse-led program, which …
Phase: NA • Sponsor: Johns Hopkins University • Aim: Prevention
Last updated Apr 26, 2026 20:00 UTC
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New walking gadget aims to help people move better
Symptom relief CompletedThis study tested a device called Gigstride in 44 adults who have trouble walking due to leg problems like arthritis, multiple sclerosis, or foot drop. Researchers wanted to see if people found it comfortable and easy to use, and if it helped with walking speed, stairs, and balan…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 28, 2026 13:02 UTC
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New hope for sinus sufferers: drug shows promise in reducing symptoms
Symptom relief CompletedThis study tested whether dupilumab, an injectable drug, can improve symptoms and quality of life in adults with chronic sinusitis who do not have nasal polyps. Thirty-three participants received either dupilumab or a placebo for six months. The main goal was to see if the drug r…
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 26, 2026 20:03 UTC
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Friendly visitors may ease dementia symptoms and caregiver stress
Symptom relief CompletedThis study tested a program called MEMORI Corps, where trained older volunteers spend time with people who have dementia, doing fun and meaningful activities together. The goal was to see if this companionship could reduce loneliness, improve quality of life, and ease stress for …
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 26, 2026 20:02 UTC
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Virtual coach + health worker aims to help smokers quit and get screened
Symptom relief CompletedThis study tested whether a computer-based virtual counselor, along with support from a community health worker, could help people in public housing quit smoking and get screened for lung cancer. Five adults aged 50 or older who smoked took part. The goal was to see if the progra…
Phase: PHASE4 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 26, 2026 20:02 UTC
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New knife may make central line insertion easier and safer
Symptom relief CompletedThis study tested a new type of knife used to make the first cut when placing a central line (a large IV in a neck or chest vein). Doctors who placed the line rated how easy the knife was to use, and the study tracked problems like needing to re-cut or restart the procedure. 86 p…
Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 26, 2026 20:02 UTC
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Can better hearing ease dementia symptoms? new study says yes
Symptom relief CompletedThis study tested a new way to provide hearing care to older adults with dementia and hearing loss. Instead of audiologists, speech-language pathologists delivered the care. The goal was to see if this approach could reduce neuropsychiatric symptoms (like agitation or mood change…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 26, 2026 20:01 UTC
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New program aims to ease burden on heart failure caregivers
Symptom relief CompletedThis study tested a program for caregivers of people with advanced heart failure. The program helped caregivers build on their strengths, find purpose, and set goals for a healthier lifestyle. Researchers wanted to see if it could improve caregivers' quality of life and reduce th…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 26, 2026 20:01 UTC
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Can a simple clinic program stop dangerous low blood sugar?
Knowledge-focused CompletedThis study tested whether a new program to prevent low blood sugar (hypoglycemia) is practical and well-liked by patients, doctors, and clinic staff. It involved 35 adults with diabetes who take medications that can cause low blood sugar. The goal was to gather feedback and early…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC
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Can a 'Champion' help you find a kidney donor? new program shows promise
Knowledge-focused CompletedThis study tested a program that teaches kidney transplant patients and their family/friends about kidney disease, transplantation, and live donation. The goal was to help patients find a live donor by having a 'champion' spread the word. 111 patients on the waitlist took part, a…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:00 UTC