Johns Hopkins University

This study looks at three strategies to help people who inject drugs in India control their HIV: starting treatment the same day, receiving care at community centers instead of government clinics, and getting extra support if the first treatment doesn't work. About 800 participan…

This study tests a procedure called FETO for unborn babies with a severe form of left congenital diaphragmatic hernia (CDH), a birth defect where the diaphragm doesn't form properly, causing organs to move into the chest and compress the lungs. The procedure involves placing a ti…

This study compares two approaches for treating relapsing-remitting multiple sclerosis: starting with a strong, high-efficacy drug early on versus starting with a milder first-line therapy and switching to a stronger one only if needed. The goal is to see which strategy better pr…

This study tests whether changing the type of fat eaten or adding a statin can safely lower high cholesterol in 22 adults with epilepsy who have been on a modified Atkins diet for at least a year. The goal is to reduce heart disease risk without causing more seizures or making it…

This study tests advanced ultrasound techniques to make breast images clearer and help doctors spot important features like cysts and tiny calcium deposits. Researchers will compare new methods with standard ultrasound, and also test a combined ultrasound-and-light approach. Abou…

This study tests whether a gentle brain stimulation technique called tDCS can improve depression and other non-motor symptoms in people with Parkinson's disease. About 80 participants will receive either real or fake stimulation over 10 sessions. The goal is to see if this safe, …

This study collects blood and tumor tissue from 360 early-stage liver cancer patients who had surgery to remove their cancer. Researchers look for specific immune system markers and antibodies that might signal whether the cancer will come back. The goal is to better understand w…

This study looks at how aging changes our ability to become aware of patterns during a simple learning task. Researchers used a mild electrical current on the scalp to temporarily disrupt a brain area in 16 healthy adults aged 20-30. They then measured awareness of a tone-air puf…

This study was designed to see how different drugs and drug combinations change mood, pain tolerance, and mental performance in healthy adults aged 18 to 55. Researchers planned to measure how much of a blinded drug people would take when it was free, and the highest price they w…

This study looks at whether the type of anesthesia (general vs. spinal) affects the risk of bone cement implantation syndrome (BCIS) in 24 adults having hip fracture surgery. BCIS can cause dangerous drops in blood pressure and oxygen levels. The goal is to see if spinal anesthes…

This study from Johns Hopkins University explores whether a simple video recording can accurately measure vital signs like blood oxygen levels. Researchers will compare video data with standard contact sensors in 94 healthy adults. The goal is to make telemedicine visits more eff…

This small early-phase study at Johns Hopkins University is testing whether a cream made from sulforaphane, a compound found in broccoli, can improve skin aging and protect against damage from ultraviolet (UV) and visible light. Twelve adults with healthy or moderately aged skin …