Jazz Pharmaceuticals

This study tested a drug called ZW25 (zanidatamab) in 87 people with advanced bile duct cancer that has too much HER2 protein. The goal was to see if the drug could shrink tumors. Participants had already tried at least one other chemotherapy. The study is complete, and results w…

This study observed 272 adults with extensive-stage small cell lung cancer who were already receiving the drug Zepzelca as part of their routine care. Researchers tracked how well the drug shrank tumors and how long patients lived, while also monitoring side effects. The goal was…

This study tested whether combining two drugs, zanidatamab and evorpacept, is safe and can shrink tumors in people with advanced HER2-expressing cancers (cancers that have too much of a protein called HER2). The trial included 52 adults whose cancer had spread or could not be rem…

This study tested a new drug called ZW25 (zanidatamab) combined with standard chemotherapy in 74 people with advanced HER2-positive stomach, bile duct, or colorectal cancers. The goal was to see if the combination is safe and can shrink tumors. Results showed some patients had th…

This study measured how blood pressure changed when 155 adults with narcolepsy switched from a high-sodium medicine (sodium oxybate) to a low-sodium version (Xywav). The goal was to see if the switch lowered blood pressure. Participants were already taking the high-sodium drug an…

This study looked at whether adding Epidiolex (a CBD-based medicine) to usual treatment can improve behavior, sleep, and quality of life in people aged 1 to 65 with tuberous sclerosis complex (TSC) who have seizures. Researchers tracked changes in behavior, seizure frequency, and…

This study tested a drug called suvecaltamide in 169 adults with Parkinson's disease whose hand or arm tremors were still bothersome despite their usual medications. The goal was to see if the drug could reduce tremor severity and improve daily activities like eating and dressing…

This study looked at 113 adults in Italy with certain types of acute myeloid leukemia (AML) who were treated with Vyxeos liposomal as part of their normal care. Researchers tracked how many patients achieved complete remission without signs of the disease after treatment. The goa…