Real-World italian study tracks vyxeos Liposomal's impact on Tough-to-Treat AML

NCT ID NCT06143839

Completed Knowledge-focused Sponsor: Jazz Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study observed 113 adults in Italy with acute myeloid leukemia (AML) linked to prior cancer therapy or bone marrow problems. All participants received Vyxeos liposomal as part of their normal care. Researchers tracked how many achieved complete remission without detectable disease after treatment. The goal was to see how well the drug works outside of controlled clinical trials.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia acute myeloid leukemia with multilineage dysplasia therapy-related myeloid neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE MYELOID LEUKEMIA (AML) ACUTE MYELOID LEUKEMIA WITH MYELODYSPLASIA-RELATED CHANGES THERAPY-RELATED ACUTE MYELOID LEUKEMIA

Contacts and locations

Locations

Azienda Ospedaliera Universitaria Federico II

Naples, 80131, Italy
Azienda ospedaliera Santi Antonio e Biagio e Cesare Arrigo

Alessandria, 15121, Italy
Istituto Oncologico Veneto

Castelfranco Veneto, 31033, Italy
Ospedale Bianchi Melacrino Morelli

Reggio Calabria, 89124, Italy
Ospedale Busto Arsizio

Busto Arsizio, 21052, Italy
Ospedale Cardarelli

Naples, 80131, Italy
Ospedale Careggi

Florence, 50134, Italy
Ospedale Civile Santo Spirito

Pescara, 65124, Italy
Ospedale Papa Giovanni XXIII

Bergamo, 24127, Italy
Ospedale Riuniti Marche Nord

Torrette Ancona, 60126, Italy
Ospedale Sant'Eugenio

Roma, 00144, Italy
Ospedale Santa Chiara

Pisa, 56126, Italy
Ospedale Vito Fazzi

Lecce, 73100, Italy
Ospedale di Bolzano

Bolzano, 39100, Italy
Ospedale di Ravenna

Ravenna, 48100, Italy
Ospedale di Trieste

Trieste, 34129, Italy
Ospedali Riuniti Villa Sofia Cervello

Palermo, 90146, Italy
Policlinico Agostino Gemelli

Roma, 00168, Italy
Policlinico Molinette

Torino, 10126, Italy
Policlinico San Martino

Genova, 16132, Italy
Policlinico Sant'Orsola

Bologna, 40138, Italy
Policlinico Tor Vergata

Roma, 00133, Italy
Policlinico Umberto I

Roma, 00161, Italy
Policlinico di Milano Ospedale Maggiore

Milan, 20127, Italy

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