Epidiolex shows promise for easing seizures and behavior issues in TSC
NCT ID NCT05864846
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether adding Epidiolex (a CBD-based medicine) to usual treatment can improve seizures, behavior, sleep, and quality of life in people aged 1 to 65 with tuberous sclerosis complex (TSC). 79 participants took the drug and were monitored for changes in symptoms and daily functioning. The goal was to see if Epidiolex helps with the full range of TSC-related challenges, not just seizures.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Alberta Children's Hospital
Calgary, Alberta, T3B 6AB, Canada
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Atrium Health Wake Forest Baptist Medical Center
Winston-Salem, North Carolina, 27157, United States
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BC Children's Hospital
Vancouver, British Columbia, V6H 3V4, Canada
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Evelina London Children's Hospital Guys St Thomas' NHS Foundation Trust, the Guy's Hospital
London, England, SE1 7EH, United Kingdom
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Le Bonheur Children's Hospital
Memphis, Tennessee, 38103, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Minnesota Epilepsy Group
Roseville, Minnesota, 55113, United States
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Nicklaus Children's Health, Miami
Miami, Florida, 33155, United States
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Sheffield Children's NHS Foundation Trust
Sheffield, 2TH, United Kingdom
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The Children's Memorial Health Institute
Warsaw, 04-736, Poland
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The Hospital for Sick Children
Toronto, Ontario, M5G 1X8, Canada
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University Hospitals Bristol NHS Foundation Trust
Bristol, BS1 3NU, United Kingdom
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University of Florida Health - Department of Neurology
Gainesville, Florida, 32608, United States
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University of Texas Health Science Center - San Antonio
San Antonio, Texas, 78229, United States
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University of Texas Health Science Center at Houston - Clinical Research Unit
Houston, Texas, 77030, United States
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University of Virginia, Charlottesville
Charlottesville, Virginia, 22903, United States
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Yale University School of Medicine
New Haven, Connecticut, 06519, United States