Insightec

This early-phase study tested whether a special ultrasound device can safely open the blood-brain barrier in people with recurrent glioblastoma, a serious brain cancer. The goal was to let the chemotherapy drug carboplatin reach the tumor more effectively. Twenty-eight participan…

This study tested the safety of using focused ultrasound to create a small lesion in the brain area that controls movement, aiming to reduce Parkinson's symptoms like tremor and stiffness. Seven people with advanced Parkinson's took part. The goal was to see if the procedure is s…

This study tested a two-stage ultrasound treatment for people with severe hand tremors that medication couldn't control. Seven participants received the treatment on one side of the brain first, then on the other side at least nine months later. The goal was to see if the staged …

This study tested whether a device called ExAblate can safely and repeatedly open the blood-brain barrier in 20 patients with high-grade glioma (a serious brain cancer) who were already receiving standard chemotherapy. The goal was to allow more chemotherapy to reach the tumor. T…

This study tested a device that uses focused ultrasound to temporarily open the blood-brain barrier in 35 people with Alzheimer's disease. The goal was to see if this procedure is safe and could help treatments reach the brain more effectively. Participants were between 50 and 85…

This study tested whether a focused ultrasound device can safely and temporarily open the blood-brain barrier in 20 people with mild-to-moderate Parkinson's disease dementia. The goal was to see if this approach is safe and feasible, not to cure the disease. Participants were mon…

This study tested whether using focused ultrasound to temporarily open the blood-brain barrier is safe for people with Her2-positive breast cancer that has spread to the brain. Eight participants received the treatment, and researchers monitored for side effects and checked if th…

This early study tested whether a device using focused ultrasound can safely open the blood-brain barrier in 3 patients with high-grade glioma (a type of brain cancer) who were receiving standard chemotherapy. The goal was to let more chemo reach the tumor. The study focused on s…

This study tested a new way to treat movement problems in Parkinson's disease using focused sound waves (ExAblate) to target a small area in the brain. Thirty-six adults with Parkinson's whose symptoms were not well controlled on one side of the body received either the real trea…

This study tested a new way to treat hand tremors in people with Parkinson's disease who don't get enough relief from medication. Using focused ultrasound waves, doctors created a small lesion in the brain to stop the tremor. Ten participants were treated and followed for up to o…

This early study tested whether a special ultrasound technique could safely open the blood-brain barrier in the motor area of the brain in 4 people with ALS. The goal was to see if the procedure was safe and possible, not to treat the disease. Researchers measured side effects an…

This small pilot study tested whether a technique called MR-guided focused ultrasound could safely open the blood-brain barrier to deliver the drug Cerezyme into the brains of 4 people with Parkinson's disease. The main goal was to see if the barrier could be opened successfully,…