Huazhong University Of Science And Technology

This Phase 2 trial tests whether adding zanubrutinib to standard chemotherapy (R-CHOP) can better treat newly diagnosed diffuse large B-cell lymphoma that shows p53 protein expression. About 41 adults aged 18–75 will receive the combination. The main goal is to see how many patie…

This study is testing whether taking vitamin D3 or yeast beta-glucan daily for two years can improve blood sugar control and lower the 10-year risk of heart disease in 2,500 adults aged 40–79 with type 2 diabetes. Participants will be randomly assigned to receive one of the suppl…

This study is testing an artificial intelligence model called Cyst-AI that uses endoscopic ultrasound images and patient data to help doctors tell apart different types of pancreatic cysts. The goal is to improve diagnosis and guide treatment decisions. Researchers plan to enroll…

This study compares robotic ultrasound to traditional sonographer-led screening for breast cancer in 70,000 women aged 35-64. The goal is to see if the robot can detect cancer just as well and whether women follow up on recommended care. Participants will get a breast ultrasound …

This study is testing whether switching from solid fuels (like coal or wood) to cleaner liquefied petroleum gas (LPG) stoves, and adding kitchen ventilation fans, can reduce indoor air pollution and improve heart and lung health. About 1,200 households in China will be split into…

This study tests whether taking vitamin D and prebiotics (inulin) during early pregnancy can help control blood sugar in women at high risk for gestational diabetes. 500 pregnant women will receive supplements or placebos from 6-15 weeks of pregnancy. The goal is to see if these …

This study tests three different numbing medicine combinations for pain after total knee replacement. 90 adults having knee surgery will get one of three options: a long-acting numbing drug, or a standard numbing drug plus one of two additives. The goal is to see which approach r…

This study is testing the smallest amount of the anesthetic ropivacaine needed to numb the arm for hand and forearm surgery using a targeted nerve block. Researchers will inject decreasing doses around the C7 nerve root in the neck and check how well it blocks sensation and movem…

This study tests whether a long-acting form of the anesthetic bupivacaine, combined with regular bupivacaine, can control pain better than the standard drug ropivacaine after hip replacement. Sixty adults with hip fractures or necrosis will receive one of the two treatments via a…

This study tests whether acupuncture can improve pregnancy rates for women who have had multiple failed IVF attempts. About 771 women will be split into three groups: real acupuncture plus IVF, fake (sham) acupuncture plus IVF, or IVF alone. The goal is to see if adding acupunctu…

This study is testing whether two dietary supplements, urolithin A and fisetin, can improve sleep quality and reduce signs of aging in middle-aged and older adults. Eighty participants aged 30-75 with poor sleep will take one of the supplements, a combination, or a placebo daily …

This study aims to find blood markers that could predict delirium—a state of sudden confusion—after heart surgery. Researchers will measure certain proteins and other substances in the blood of 113 patients before and after surgery. The goal is to develop a simple test to identif…

This study tests a new device that measures how relaxed a patient's muscles are during surgery. The goal is to see if it works as well as the standard monitor, but is easier to set up and use. About 100 adults having planned surgery will take part. The study does not test a treat…

This study looks at whether monitoring brain waves (EEG) during heart surgery can help predict and understand postoperative delirium, a common complication causing confusion. Researchers will follow 200 adults undergoing cardiovascular surgery, using EEG to track brain activity a…

This study is watching 400 children under 16 who are having planned surgery. Researchers will use a special brain wave test (EEG) to see if they can predict which kids will wake up confused or agitated (emergence delirium). The goal is to better understand why this happens and ho…

This study looks at brain wave patterns in 250 adults during anesthesia to find better ways to measure how deep their unconsciousness is. Current monitors don't work well with all anesthetics, so researchers hope to create a more reliable system. Participants will have their brai…