Can vitamin d and yeast fiber tame diabetes and protect the heart?

NCT ID NCT06861062

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether taking vitamin D3 or yeast beta-glucan daily for two years can improve blood sugar control and lower the 10-year risk of heart disease in 2,500 adults aged 40–79 with type 2 diabetes. Participants will be randomly assigned to receive one of the supplements or a placebo, and researchers will track changes in HbA1c and heart risk scores. The goal is to find a simple, low-cost way to help manage diabetes and prevent complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vitamin D3 (cholecalciferol) and yeast beta-glucan

What this could lead to

If it works, this could show that simple daily supplements help manage blood sugar and lower heart disease risk in people with type 2 diabetes.

What could go wrong

This is a large but early-stage trial with no phase designation. Supplements may have only small effects, and results may not apply to everyone with diabetes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Guangxi Medical College

    RECRUITING

    Nanning, Guangxi, China

    Contact

  • Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kailuan General Hospital

    RECRUITING

    Tangshan, Hebei, China

    Contact

  • Sichuan University

    RECRUITING

    Chengdu, Sichuan, China

    Contact

  • Sinopharm Dongfeng General Hospital

    RECRUITING

    Shiyan, Hubei, China

    Contact