Hospital De Clinicas De Porto Alegre

This study looks at whether partly replacing animal protein with plant protein can improve blood sugar control in people with type 2 diabetes who are overweight. About 146 adults will follow either a plant-based diet or a standard healthy diet for 24 weeks. The main goal is to se…

This phase 2 trial tests whether taking taurine, a natural amino acid found in energy drinks and supplements, can improve blood sugar, cholesterol, and inflammation in people with type 2 diabetes. About 94 adults with diabetes will take either taurine powder or a placebo twice da…

This study compares two ways of screening for diabetic eye disease: using artificial intelligence to read retinal photos versus having eye doctors review them. About 922 adults with diabetes will get their eyes photographed in a primary care clinic. The goal is to see if AI can m…

This study tests whether a personalized diet plan from a registered dietitian can improve constipation in people with Parkinson's disease. Fifty-four participants will follow the diet for 3 months, with regular check-ins. Researchers will measure bowel movements, gut bacteria, an…

This study tests whether a type of talk therapy called Interpersonal Psychotherapy (IPT), delivered in groups by trained non-specialists, can reduce depressive symptoms in young adults aged 18-24 in Porto Alegre, Brazil. Half of the 50 participants will receive the 8-week group t…

This study compares a home-use brain stimulation device (tDCS) to the drug duloxetine for treating fibromyalgia in 610 women. Participants use the device daily for 4 weeks or take duloxetine, both combined with exercise and pain education. The goal is to see if tDCS works as well…

This study tests whether a special blue light device can improve mood in women who are 4-6 weeks postpartum and have depression or anxiety. Half of the 50 depressed participants will use the blue light, the other half a dim placebo light. The researchers will also track sleep and…

This study tests whether giving doctors a geriatric assessment—a quick check of frailty and function—helps them set safer blood sugar goals for patients aged 60+ with type 2 diabetes. 220 participants will be randomly assigned to usual care or to have their doctor receive the ass…

This study looks at whether people with stable heart failure whose heart function has improved can safely stop taking a type of medication called a mineralocorticoid antagonist (MRA). Researchers will monitor 90 participants over 24 weeks to see if stopping the drug leads to a de…

This study tests an artificial intelligence (AI) algorithm that helps decide whether a patient's referral to a specialist is urgent or can be handled in primary care. About 934 referrals from the Brazilian state of Rio Grande do Sul will be randomly assigned to either the AI or t…