Hospital De Clinicas De Porto Alegre

This trial tests whether a daily routine of tummy time and careful positioning can help correct cranial asymmetry—a flattened head shape—in premature newborns. About 300 babies born before 37 weeks who are in the neonatal ICU or intermediate care unit will be split into two group…

This trial investigates whether a high-protein diet, with or without an HMB supplement, can improve muscle mass, strength, and physical function in people with heart failure. Participants are randomly assigned to one of three groups: a standard-protein diet, a high-protein diet, …

This study tests whether using a special ultrasound score (DUCS) to guide diuretic dosing can improve outcomes for people hospitalized with acute heart failure. About 128 adults with heart failure and fluid buildup will be randomly assigned to either standard care or ultrasound-g…

This study compares a rapid test that identifies pneumonia-causing bacteria in about one hour to standard lab methods that take 2-4 days. Researchers want to see if the faster test helps doctors choose the right antibiotics sooner for 150 hospitalized patients with pneumonia. The…

This trial tests whether a paravertebral block—a numbing medicine delivered near the spine—can control pain after open chest surgery just as well as the standard epidural block. Adults having elective thoracotomy will be randomly assigned to one of the two blocks, and their pain …

This study compares two ways to drain blocked bile ducts in people with cancer near the liver. One method places a tube across the blockage into the intestine, while the other uses a metal stent that stops short of the intestine. The goal is to see which approach causes fewer com…

This phase 2 trial tests whether a single infusion of tocilizumab, a drug that blocks the inflammatory molecule IL-6, can reduce depressive symptoms in 32 adults with treatment-resistant major depression. Participants must have high inflammation levels (CRP ≥3 mg/L) and will rece…

This study compares two types of IV catheters in 104 newborns with congenital syphilis who need 10 days of antibiotics. One group gets a standard short catheter, the other a longer catheter placed using ultrasound by a specialized nurse. The goal is to see which lasts longer and …

This trial explores whether shining low-level light on the scalp—a technique called transcranial photobiomodulation—can change brain activity and improve fine motor skills like finger tapping. Twenty healthy young adults will receive different light pulse frequencies (continuous,…

This study explores whether shining near-infrared light on the scalp — a technique called transcranial photobiomodulation — can change how the brain controls movement. Twenty healthy adults aged 18 to 35 will receive light at different pulse frequencies (continuous, 10 Hz, 40 Hz,…

This study will compare five versions of a school-based training program to see which best helps teachers recognize and respond to students' mental health needs. About 2,925 public school teachers in Brazil will take part in in-person, online, or self-paced training, with some gr…

This study looks at how social and economic factors—like income and neighborhood—affect recovery and survival after surgery. Researchers will study 45,000 patients in Brazil to see if those facing more hardship have worse outcomes. The goal is to identify vulnerable patients and …

This study will create and test a tracking program to help elderly people (60+) who have two or more chronic conditions after they leave the hospital. The goal is to see if this guidance improves how well they follow their own care plans. About 148 participants will be enrolled, …