Protein power: could a diet boost help heart failure patients keep their muscle?

NCT ID NCT07731048

Not yet recruiting Disease control Sponsor: Hospital de Clinicas de Porto Alegre Source: ClinicalTrials.gov ↗

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial investigates whether a high-protein diet, with or without an HMB supplement, can improve muscle mass, strength, and physical function in people with heart failure. Participants are randomly assigned to one of three groups: a standard-protein diet, a high-protein diet, or a high-protein diet plus HMB. The study aims to see if these nutritional interventions offer benefits beyond standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a dietary supplement called beta-hydroxy-beta-methylbutyrate (HMB)
What this could lead to: If it works, this could point toward a simple nutritional strategy to help heart failure patients maintain muscle and physical function.
What could go wrong: This is a small, early-stage trial with only 84 participants. The benefits may be modest or not translate to real-world improvements.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

Locations

Hospital de Clínicas de Porto Alegre (Clinical Research Center)

Porto Alegre, Rio Grande do Sul, Brazil

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