Genentech, Inc.

This study tested a new drug called mosunetuzumab, both alone and combined with another drug (atezolizumab), for people with B-cell non-Hodgkin lymphoma or chronic lymphocytic leukemia that had come back or stopped responding to prior treatments. The main goals were to find safe …

This study tested whether adding a personalized cancer vaccine (autogene cevumeran) to standard immunotherapy (pembrolizumab) works better than immunotherapy alone for people with advanced melanoma that hasn't been treated before. The trial involved 131 patients with advanced ski…

This study tested whether adding a new drug called tiragolumab to an existing immunotherapy (atezolizumab) works better than the standard immunotherapy alone. It involved 135 people with advanced non-small cell lung cancer who had not yet received chemotherapy. The goal was to se…

This early-stage trial tested a new drug called cevostamab in 355 patients whose multiple myeloma had returned or stopped responding to other treatments. The main goal was to find safe dosage levels and understand how the drug moves through the body. Researchers monitored side ef…

This early-stage study tested the safety of a new drug called GDC-1971 when given alongside standard cancer medications. It involved 10 patients with advanced lung or colorectal cancer whose disease had progressed despite previous treatments. The main goal was to find a safe dose…

This study tested whether adding a new drug called astegolimab to standard COPD medications could help reduce the number of serious flare-ups. It involved over 1,300 adults with COPD who were former or current smokers and had a history of frequent flare-ups. The main goal was to …

This study looked at how well the approved MS drug ocrelizumab works to control disease activity in Black and Hispanic patients with relapsing multiple sclerosis. Researchers followed 179 patients for 48 weeks to see if the treatment prevented relapses, disability progression, or…

This study tested an investigational drug called GDC-6599 to see if it could reduce the frequency and severity of chronic cough in adults. It involved 49 participants whose cough was linked to conditions like asthma or chronic obstructive pulmonary disease (COPD) and had lasted f…

This study tested whether an injectable drug called vixarelimab (KPL-716) could safely reduce severe itching and improve skin lesions in adults with prurigo nodularis. About 240 participants with moderate to severe symptoms received either the drug or a placebo for 8 to 16 weeks …

This study aimed to understand how a drug called divarasib is processed in people with different levels of liver problems compared to healthy people. It involved 31 participants, some with healthy livers and some with mild, moderate, or severe liver impairment. The main goal was …

This early-stage study tested how the body absorbs a new drug called ZN-A-1041. Researchers compared how much of the drug got into the bloodstream when it was given as different types of pills versus a capsule. The study also planned to check if food or another stomach medicine a…

This study aimed to understand how safe and comfortable different ways of giving immunoglobulin G (IgG) injections under the skin are. It involved 82 healthy volunteers who received injections under varying conditions. The main goal was to measure pain, skin reactions, and overal…