Comfort check: how do different injection methods for IgG stack up?

NCT ID NCT07025577

Completed Knowledge-focused Sponsor: Genentech, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested how well healthy adults tolerate immunoglobulin G (IgG) injections given under the skin using different techniques. Researchers measured pain, injection-site reactions, and fluid leakage in 82 participants. The goal was to find the most comfortable and safe way to deliver IgG, which is used to treat immune disorders.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Immunoglobulin G (IgG)
What this could lead to: If successful, this could help make future IgG injections more comfortable for patients who need regular doses.
What could go wrong: This is an early-phase study in healthy volunteers, not patients. Results may not apply to real-world use, and side effects like injection-site pain or reactions are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY PARTICIPANTS

Contacts and locations

Locations

Daytona Beach Clinical Rsch Unit

Daytona Beach, Florida, 32117, United States
Fortrea Clinical Research Unit - Dallas

Dallas, Texas, 75247-4989, United States
Fortrea Clinical Research Unit Inc. - Madison

Madison, Wisconsin, 53704-2526, United States

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