Liver function and drug processing: a closer look at divarasib

NCT ID NCT06734208

First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 33 times

Summary

This study looked at how the drug divarasib is processed in the bodies of 31 people with different levels of liver function, from healthy to severely impaired. Participants received a single dose, and researchers measured drug levels in the blood over time. The goal was to understand how liver health affects drug clearance, not to treat any disease.

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Contacts and locations

Locations

  • American Research Corporation Inc.

    San Antonio, Texas, 78215, United States

  • Clinical Pharmacology of Miami, Inc.

    Miami, Florida, 33014, United States

  • Orlando Clinical Research Center

    Orlando, Florida, 32809, United States

  • Panax Clinical Research, LLC

    Miami Lakes, Florida, 33014, United States

Conditions

The condition(s) this trial relates to.

liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.