New drug combo targets Hard-to-Treat cancers

NCT ID NCT04250155

First seen Jan 05, 2026 · Last updated May 01, 2026 · Updated 17 times

Summary

This study tests a new experimental drug called XmAb24306, given alone or with another drug (atezolizumab), in people with advanced solid tumors that cannot be cured. The main goal is to check safety and find the best dose. About 195 adults with various solid tumors will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Asan Medical Center - PPDS

    Seoul, 05505, South Korea

  • City of Hope Comprehensive Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • Clinica Universidad de Navarra-Madrid

    Madrid, 28027, Spain

  • Clinica Universitaria de Navarra

    Pamplona, Navarre, 31008, Spain

  • Fondazione IRCCS Istituto Nazionale dei Tumori

    Milan, Lombardy, 20133, Italy

  • GasthuisZusters Antwerpen

    Wilrijk, Antwerp, 2610, Belgium

  • Het Nederlands Kanker Instituut Antoni Van Leeuwenhoek Ziekenhuis

    Amsterdam, North Holland, 1066 CX, Netherlands

  • Honor Health Research Institute

    Scottsdale, Arizona, 85258, United States

  • Hospital Clinico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital de Clinicas de Porto Alegre HCPA PPDS

    Porto Alegre, Rio Grande do Sul, 90560-030, Brazil

  • Instituto do Cancer do Estado de Sao Paulo - ICESP

    São Paulo, 01246-000, Brazil

  • Istituto Clinico Humanitas

    Rozzano, Lombardy, 20089, Italy

  • Istituto Europeo Di Oncologia

    Milan, Lombardy, 20141, Italy

  • Parkville Cancer Clinical Trial Unit (PCCTU)

    Melbourne, Victoria, 3000, Australia

  • Princess Margaret Hospital

    Toronto, Ontario, M5G 2M9, Canada

  • SCRI Oncology Partners

    Nashville, Tennessee, 37203, United States

  • START Madrid-FJD, Hospital Fundacion Jimenez Diaz

    Madrid, 28040, Spain

  • Samsung Medical Center - PPDS

    Seoul, 06351, South Korea

  • Seoul National University Bundang Hospital

    Seongnam-si, 13620, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital Yonsei University Health System - PPDS

    Seoul, 03722, South Korea

  • Stanford Health Centre - Palo Alto

    Palo Alto, California, 94304, United States

  • Universitair Medisch Centrum Groningen

    Groningen, 9713 GZ, Netherlands

  • University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center

    San Francisco, California, 94158-2545, United States

  • Yale University

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.