Fondazione Irccs Policlinico San Matteo Di Pavia
Clinical trials sponsored by Fondazione Irccs Policlinico San Matteo Di Pavia, explained in plain language.
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Scientists Fine-Tune cancer drug mix to protect patients from infections
Disease control CompletedThis study aimed to find the safest way to combine three medications for older adults with acute myeloid leukemia (AML), a type of blood cancer. Researchers tested a standard cancer drug combination (HMA + venetoclax) along with an antifungal drug (posaconazole) to prevent infect…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Inhaled nanoparticles target scarring in transplanted lungs
Disease control CompletedThis research tested a new experimental treatment for chronic lung rejection (BOS) that can occur after a lung transplant. The treatment uses tiny particles (liposomes) designed to carry an existing drug (everolimus) directly into the lungs via an inhaler. The goal is to target t…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Timing is everything: when to remove the gallbladder after pancreatitis attack
Disease control CompletedThis study looked at whether it's better to remove the gallbladder immediately during the same hospital stay or to wait several weeks after a mild gallstone pancreatitis attack. Researchers followed 445 patients to see which timing leads to fewer repeat gallstone problems and com…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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New ultrasound tests could replace liver biopsies
Diagnosis CompletedThis study compared different ultrasound techniques for measuring liver stiffness, which helps doctors assess liver disease without invasive biopsies. Researchers tested 72 adults using both established and newer ultrasound methods to see which worked best. The goal was to find m…
Phase: NA • Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Diagnosis
Last updated Mar 31, 2026 12:11 UTC
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New ultrasound tech aims to spot fatty liver disease
Diagnosis CompletedThis study tested new software on standard ultrasound machines to see how well it measures fat in the liver. Researchers compared the results from different ultrasound devices to a specialized test called CAP, which is already used for this purpose. The goal was to see if the new…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Diagnosis
Last updated Mar 30, 2026 14:34 UTC
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Can new rules save mothers from sepsis?
Knowledge-focused CompletedThis study checked if new regional guidelines for spotting and treating sepsis in pregnant and postpartum women worked. Researchers compared hospital stays and health outcomes for 52 women before and after the guidelines were introduced. The goal was to see if standardized care c…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:40 UTC
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Scientists hunt clues in blood to unlock new treatment path for bone marrow cancer
Knowledge-focused CompletedThis completed study aimed to understand how a specific type of immune cell, called myeloid-derived suppressor cells (MDSCs), contributes to the chronic inflammation and blood vessel growth seen in primary myelofibrosis, a serious bone marrow cancer. Researchers studied blood and…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Do COVID drugs work for cancer patients? Real-World study investigates
Knowledge-focused CompletedThis study looked at how well early COVID-19 treatments work for people who also have cancer and are receiving cancer therapy. Researchers followed 112 cancer patients to see if these COVID-19 drugs helped them avoid hospitalization and recover faster. The goal was to gather real…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Do hospital antibiotics put kids at risk for superbug?
Knowledge-focused CompletedThis study aimed to understand the risk of children picking up a drug-resistant germ called MRSA while in the hospital. Researchers tracked 581 hospitalized children aged 1 to 16 to see how many developed MRSA in their noses within 30 days. A key goal was to see if receiving anti…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:27 UTC
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Doctors track transplant patients to uncover hidden risks
Knowledge-focused CompletedThis study created a registry to track 60 heart transplant patients over time. The goal was to collect detailed information to understand the main causes of death, hospitalization, and health problems after a transplant. By analyzing this data, doctors aimed to improve outpatient…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Researchers track teen anxiety and test counseling program
Knowledge-focused CompletedThis study aimed to understand the mental and emotional state of 80 teenagers (ages 14-17) experiencing psychological distress. Researchers measured their anxiety and distress levels and then offered a 10-session counseling program to those who needed it. The goal was to see how …
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Can talking it out help ease the heavy burden on our frontline healthcare heroes?
Knowledge-focused CompletedThis study aimed to understand and measure 'compassion fatigue'—a mix of burnout and work-related stress—in doctors, nurses, and assistants working in the Emergency Room and Intensive Care Unit. Researchers surveyed 159 staff members, held group discussions over 18 months, and th…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Mar 12, 2026 13:51 UTC
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Scientists search for hidden cause of leukemia relapse
Knowledge-focused CompletedThis study aimed to understand why some patients with a specific, often treatable type of acute myeloid leukemia (AML) still relapse. Researchers analyzed bone marrow cells from 70 patients to see if certain cells in the bone marrow environment help leukemia cells survive treatme…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:25 UTC