Fondazione Irccs Policlinico San Matteo Di Pavia

This study tested a new way to deliver the drug everolimus directly to the lungs using tiny particles called liposomes. The goal was to treat chronic lung rejection (bronchiolitis obliterans syndrome) after a lung transplant. Researchers worked with cells and lung tissue from 19 …

This study tested new software on ultrasound machines to measure liver fat in people with non-alcoholic fatty liver disease (NAFLD). The goal was to see if these ultrasound results matched the standard Fibroscan test. 25 adults took part. The approach is non-invasive and could ma…

This study looked at whether a shot of Evusheld (two long-acting antibodies) could prevent COVID-19 in 88 immunocompromised people who did not make enough antibodies after vaccination. Participants were observed for symptomatic infections. The goal was to see if this preventive a…

This small study tested whether citicoline, a natural brain chemical, could improve vision in 6 glaucoma patients after eye surgery. The goal was to see if adding citicoline to standard surgery helps protect the optic nerve and enhance visual function. Results are not yet availab…

This study looked at how many children aged 1 to 16 years old develop MRSA (a hard-to-treat bacteria) in their nose while staying in the hospital. Researchers also compared children who received antibiotics with those who did not. The goal was to understand if antibiotic use incr…

This study looked at compassion fatigue, burnout, and stress in 159 healthcare workers in emergency rooms and intensive care units. Researchers measured their well-being before and after they took part in group discussions aimed at finding ways to cope. The goal was to understand…

This completed study involved 250 people with AL amyloidosis, a rare disease where abnormal proteins build up in organs. Researchers analyzed blood and bone marrow samples to find biological markers that could predict how well patients respond to first-line therapies. The goal is…

This study looked at 70 people—some with primary myelofibrosis (a rare bone marrow disorder) and some healthy—to understand how certain immune cells called MDSCs fuel inflammation and blood vessel growth in the disease. Researchers measured these cells in blood and spleen samples…

This study used computer simulations to compare three types of radiation (photons, protons, and carbon ions) for treating a dangerous heart rhythm called ventricular tachycardia. Researchers created treatment plans based on real heart scans from 23 patients who were scheduled for…

This study created a database of 60 heart transplant patients to track their health over time. The goal was to learn the main reasons for death, illness, and hospital stays after a heart transplant. No new treatments or medications were tested—only existing medical records and fo…

This study looked at different ultrasound techniques to measure liver stiffness in 72 adults with chronic liver disease. The goal was to see how newer methods compare to an established one. No treatment was given; the study simply compared the accuracy of the tests.

This study looked at 50 adults receiving a stem cell transplant for blood cancer. Researchers checked if the number of certain cells in the blood before transplant could predict the risk of a serious complication called graft-versus-host disease (GVHD). The goal was to see if thi…

This study looked at 445 adults with mild pancreatitis caused by gallstones. Researchers compared having gallbladder surgery during the same hospital stay versus waiting for a later date. The goal was to see if same-stay surgery reduces the chance of future gallstone problems wit…

This study looked at bone marrow cells from 70 adults with a favorable type of acute myeloid leukemia (AML) that has a mutation in the NPM1 gene. Even though these patients are expected to do well with standard treatment, more than half still relapse. Researchers wanted to see if…

This study looked at 30 people newly diagnosed with cardiac AL amyloidosis, a rare disease where abnormal proteins build up in the heart. Researchers used advanced imaging (MRI, PET, and ultrasound) along with blood tests to see which measurements best predict survival and how th…

This study looked at whether a set of standard care steps (called a sepsis bundle) could improve outcomes for pregnant or postpartum women with sepsis, a severe infection. Researchers compared 52 women treated before and after the bundle was introduced in hospitals across norther…

This study looked at 15 older adults with acute myeloid leukemia (AML) who were taking a chemotherapy combination (azacitidine or decitabine plus venetoclax) along with an antifungal drug (posaconazole) to prevent infections. The goal was to measure how posaconazole changes venet…

This study looked at 80 teenagers aged 14 to 17 who were experiencing emotional distress. Researchers measured their anxiety levels using a questionnaire and offered a 10-session counseling program to those who needed it. The goal was to better understand teen mental health and s…

This study looked at how well early COVID-19 treatments work in cancer patients who are on active cancer therapy. Researchers tracked 112 patients to see if these treatments reduced hospitalizations and helped them recover faster. The goal is to fill knowledge gaps and improve ca…