Fondazione Irccs Istituto Nazionale Dei Tumori, Milano

This trial is testing a new combination of chemotherapy drugs for people with a specific type of advanced colorectal cancer that has spread. The treatment is designed for patients whose tumors have certain genetic features. The main goals are to find the safest dose and see if th…

This study is testing if women with certain aggressive breast cancers (HER2-positive or Triple-negative) who have an excellent response to initial drug therapy can safely skip standard follow-up treatments. One group will skip surgery, and another will skip radiation. The goal is…

This study is for men whose prostate cancer has spread to a few other spots in the body but is still sensitive to hormone-blocking drugs. It aims to see if adding a direct treatment to the prostate itself—like surgery or radiation—on top of standard drug therapy is better at keep…

This study aims to create a better tool for predicting duodenal cancer risk in people with Familial Adenomatous Polyposis (FAP), a genetic condition. Researchers will analyze past endoscopy results from 300 FAP patients to develop and test a new risk classification model. The goa…

This study aims to understand if the bacteria in a patient's mouth influence how well radiation therapy works for head and neck cancer and how severe the side effects are. Researchers will collect saliva samples from about 100 patients before, during, and after their radiation tr…