Blood test may reveal hidden tumor secrets in head and neck cancer
NCT ID NCT07512921
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a simple blood test can give the same information about a tumor's biology as testing the tumor tissue itself. Researchers will collect blood samples from 300 adults with HPV-negative head and neck cancer before and after standard treatment. They will compare gene activity and other markers in the blood to those in stored tumor samples. No new drugs are tested—the goal is to see if a blood test could one day help monitor cancer after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a simple blood test that monitors tumor biology after treatment, helping doctors personalize care without repeated tissue biopsies.
What could go wrong
This is an early observational study, not a treatment trial. The blood test may not match tumor findings accurately, and results may not change current care for years.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Azienda Ospedaliera Universitaria di Sassari
RECRUITINGSassari, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fondazione IRCCS Istituto Nazionale dei Tumori
RECRUITINGMilan, 20133, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••