Chu De Reims

This study looked at children aged 3 to 15 with overactive bladder caused by nerve issues, like spina bifida. It compared two different doses of Botox injections into the bladder muscle to see if a lower dose works as well as a higher dose. The goal was to improve bladder capacit…

This study looked at whether a blood sample can find genetic changes in advanced melanoma, instead of taking a piece of the tumor with a needle or surgery. Researchers tested blood from 50 people with metastatic melanoma to see if they could spot key mutations. The goal is to mak…

This study looked at whether changes in blood pressure during a passive leg raise test can tell doctors if a patient needs more fluids. It included 39 ICU patients who were breathing on their own. The goal is to avoid giving unnecessary fluids, which can be harmful. The test uses…

This study looked at whether measuring a protein called amyloid beta 1-40 in spinal fluid can help doctors diagnose Alzheimer's disease more reliably. Current tests sometimes give unclear results. The study involved 204 people with memory problems. Researchers measured the ratio …

This study looked at 116 people with small-intestine neuroendocrine tumors (carcinoid tumors) to see if a simpler overnight urine test or a blood test could work as well as the standard 24-hour urine test for diagnosis. The standard test requires collecting all urine for 2-3 days…

This study tested whether a single osteopathic treatment in the emergency department can improve recovery from a mild to moderate ankle sprain. Fifty adults with recent sprains were randomly assigned to either standard medical care or osteopathic manipulation. Researchers measure…

This study compared two ways to manage pain after total hip replacement: a newer ultrasound-guided nerve block (PENG block) and the standard surgical infiltration. 224 adults having hip replacement took part. The goal was to see which method reduces the need for strong painkiller…

This study tested whether wearing a virtual reality headset during an epidural injection for lower back and leg pain can lower pain and anxiety. 116 adults received the injection either with or without the headset. The goal was to see if VR distraction makes the procedure more co…

This study looked at whether a type of MRI called diffusion-weighted MRI can predict if head and neck cancer will return after chemoradiotherapy. Researchers enrolled 59 patients and used the scan to measure water movement in tumors. The goal was to see if early changes could sig…

This study looked at whether a CT scan done a week after pancreatic surgery can find complications that doctors might miss. 80 adults who had planned pancreatic surgery received a CT scan before leaving the hospital. The goal was to see if the scan could detect issues like leaks …

This study used brain scans (fMRI) to understand why people with bipolar disorder sometimes have disorganized thoughts and speech. Researchers compared 79 participants—some with bipolar disorder and healthy volunteers—while they performed thinking tasks. The goal was to learn mor…

This study looked at whether certain natural infection-fighting proteins, called antimicrobial peptides, are linked to gum disease. Researchers compared mouth cell samples from 29 healthy adults and those with chronic periodontitis. The goal was to better understand what causes t…

This study looked at how well older adults with early-stage Alzheimer's can drive in real traffic. Researchers compared 60 drivers aged 70+ (half with Alzheimer's, half healthy) to find common mistakes and suggest ways to keep them driving safely. No treatment or cure was tested;…

This study looked at whether certain chemicals called organochlorines, which are stored in body fat, are linked to pancreatic cancer. Researchers compared levels of these chemicals in fat and urine samples from 56 people—some with pancreatic cancer and some without. The goal was …

This study looked at skin samples from 20 people with hidradenitis suppurativa (HS) to understand what causes inflammation in the disease. Researchers measured various inflammatory proteins in the skin to see which ones might be driving the condition. The goal was to learn more a…

This study looked at whether a protein called CD160 appears in new blood and lymph vessels in the cornea after a transplant. Researchers examined tissue from 43 adults who had corneal transplant surgery. The goal was to see if CD160 is linked to graft rejection, which could help …

This study aimed to find out how often bronchiectasis (permanent lung damage) occurs in people with primary humoral immunodeficiency, a condition that weakens the immune system. Researchers in France used CT scans to check 46 patients for lung damage that might not cause symptoms…

This study aimed to better understand hearing loss by measuring electrical signals directly from the hearing nerve during brain surgery. Nineteen participants, some with normal hearing and some with hearing loss, took part. Researchers used these detailed nerve recordings to impr…

This study explored whether certain genetic markers are linked to proliferative diabetic retinopathy (PDR), a severe eye condition that can cause blindness in people with type 2 diabetes. Researchers compared 302 patients with and without PDR to look for genetic differences. The …

This study looked at whether a specific antibody (anti-GBM) in the blood can help identify lupus patients who have kidney inflammation (lupus nephritis). Researchers tested stored blood samples from 100 people with lupus and healthy donors. The goal was to see if this antibody is…

This study looked at whether a blood test measuring elastin fragments can help doctors assess frailty in people 65 and older with cancer. Frailty affects how well patients tolerate treatment, but current methods are subjective and slow. The goal was to find a faster, more objecti…

This study looked at 100 adults on hemodialysis (kidney filtering) to understand how certain waste molecules, called AGEs, damage blood vessels and increase heart risk. Researchers measured AGE buildup in blood and skin, checked blood vessel hardening with X-rays, and analyzed ge…

This study looks at pregnancy denial, where a woman is unaware she is pregnant for months or even the whole term. Researchers want to see if this affects how mothers bond with their babies and how the child develops. They will compare 130 mothers who had pregnancy denial with tho…

This study looked at whether natural aging of proteins in the walls of blood vessels might play a role in the development of aortic aneurysms (a bulge in the main artery). Researchers collected blood and measured skin autofluorescence in 24 patients undergoing surgery for an abdo…

This study looked at whether a specific gene variation (CR1) is more common in people with Alzheimer's disease. Researchers compared 200 Caucasian adults—some with Alzheimer's and some without—to see if the gene plays a role in disease risk. No treatment was given; the goal was s…

This study looked at how children born prematurely (before 37 weeks) understand social situations and emotions compared to full-term children. Researchers tested 56 children aged 7-10 on memory, flexibility, and reading others' thoughts. They also measured parents' anxiety and st…

This study looked at 24 children with acute lymphoblastic leukemia to understand why blood clots form during early treatment. Researchers measured tiny cell fragments called microparticles, which can trigger clotting. The goal was to see if these fragments contribute to the incre…

This study looked at how well doctors, residents, and nurses check the pupils of intensive care patients compared to a special device called a pupillometer. Pupil checks are important for understanding brain health and response to medicines. The goal was to see if the manual chec…

This study looked at 125 young adults aged 18-25 to understand what makes someone more likely to binge drink. Researchers used brain scans, genetic tests, and thinking skill assessments to find patterns. The goal is to identify risk factors and guide better prevention strategies.

This study tracked 150 adults who had severe COVID-19 pneumonia to see how often they develop long-term lung damage. Researchers used CT scans to check for lung scarring and other breathing issues. The goal is to better understand the lasting effects of severe COVID-19, similar t…

This study looked at how thinking skills (like flexibility and self-control) and social understanding (like reading emotions) are linked to alcohol use disorders. Researchers tested 216 people to find early warning signs that could help improve treatment. The goal was to better u…

This study tracked 183 cancer patients receiving checkpoint inhibitors to see how often they develop autoantibodies (immune system proteins that attack the body) or autoimmune diseases. Researchers measured changes in several autoantibodies over time. The goal was to better under…

This study tested whether nurses can safely use a capnography device to guide the process of removing breathing tubes in ICU patients. Fifty adults on ventilators for over 48 hours were enrolled. The goal was to see if nurses could follow the protocol correctly, potentially reduc…

This study looked at how people with Parkinson's disease explain good and bad events in their lives, and whether deep brain stimulation (DBS) changes that. Researchers measured thinking biases in 32 patients using a questionnaire. The goal was to understand if DBS affects social …

This study looked at how the body gets rid of methotrexate, a common rheumatoid arthritis drug, in patients who take it as prescribed. Researchers measured the drug and its main byproduct in urine to create a reference range. This will help doctors identify patients who are not t…

This study tested whether Raman spectroscopy, a non-invasive laser technique, can accurately measure skin fibrosis in people with systemic sclerosis (scleroderma). Twenty-six adults with the disease had their skin scanned with the device. The goal was to see if this method is mor…

This study looked at 254 older adults to see if certain chemical changes in the blood can help identify frailty. Frailty affects many seniors and can lead to dependency, but early detection may help slow decline. Researchers measured specific markers linked to aging to find diffe…

This study looked at whether the smallest meaningful change in bone density measurements is different for people with obesity compared to those without. Researchers measured bone density twice in 120 adults with a BMI over 30. The goal was to improve accuracy of bone health tests…

This study checked 150 adults who had adrenal gland lumps found by chance, but no signs of Cushing's disease. Researchers looked for changes in a gene that controls the body's stress hormone receptor. The goal was to find out if these gene changes are more common than previously …