Children's Hospital Los Angeles
Clinical trials sponsored by Children's Hospital Los Angeles, explained in plain language.
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Computer helps kids breathe stronger, get off ventilators faster
Disease control CompletedThis study tested a new computer-based system called REDvent to help children on breathing machines. The system monitors a child's breathing effort and adjusts the ventilator to keep their breathing muscles working normally. Researchers wanted to see if this approach could preven…
Phase: NA • Sponsor: Children's Hospital Los Angeles • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New hope for kids with tough brain tumors: pill shows promise
Disease control CompletedThis study tested an oral drug called MEK162 in children whose low-grade brain tumors had come back or grown after standard treatment. The main goals were to find a safe dose for kids and to see if the drug could shrink these tumors. About 105 children took the pill twice a day f…
Phase: PHASE1, PHASE2 • Sponsor: Children's Hospital Los Angeles • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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Teens tackle weight loss from home in new virtual group study
Disease control CompletedThis study tested if a weight management program delivered through virtual group video calls could work for teens with obesity. Researchers compared teens who attended 12 online sessions over 6 months to teens who received standard in-person clinic care. The goal was to see if th…
Phase: NA • Sponsor: Children's Hospital Los Angeles • Aim: Disease control
Last updated Mar 09, 2026 14:25 UTC
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Can home visits and free water fight obesity in families?
Prevention CompletedThis study tested whether a home-based education program could help prevent obesity in Hispanic mothers and their infants. Researchers worked with 211 mother-baby pairs, providing education about reducing sugary drinks and, for some families, delivering bottled water to their hom…
Phase: NA • Sponsor: Children's Hospital Los Angeles • Aim: Prevention
Last updated Apr 01, 2026 14:42 UTC
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New training aims to ease stress for parents of seriously ill children
Symptom relief CompletedThis study tested a training program to teach problem-solving skills to parents of children undergoing a stem cell transplant. Researchers wanted to see if the program was practical for families to use and if it helped reduce parents' stress, anxiety, and depression. They compare…
Phase: NA • Sponsor: Children's Hospital Los Angeles • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Fitness trackers fight fatigue: app helps young cancer patients get moving
Symptom relief CompletedThis study tested whether a mobile health program could help adolescents and young adults with acute lymphoblastic leukemia (ALL) reduce their sitting time during maintenance chemotherapy. Twenty participants used fitness trackers with movement reminders, received coaching, and j…
Phase: NA • Sponsor: Children's Hospital Los Angeles • Aim: Symptom relief
Last updated Mar 16, 2026 15:26 UTC