New computer tool aims to keep Kids' diaphragms strong on ventilators
NCT ID NCT03266016
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested a computer program called REDvent that helps doctors set ventilators to match a child's natural breathing effort. The goal was to prevent the diaphragm from weakening while on a breathing machine. Researchers enrolled 248 children with lung disease who needed ventilation. The program used real-time measurements to adjust support, and the team tracked muscle strength and time on the ventilator.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Computerized ventilator protocol (REDvent)
- What this could lead to
- If successful, this approach could reduce the time children spend on ventilators and lower the risk of breathing muscle weakness.
- What could go wrong
- This is a Phase II trial with a moderate sample size; results may not confirm benefit in larger studies. The intervention is complex and may not work for all children.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DIAPHRAGM DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Breathing therapy may improve lung function in ventilated kids
- Computer coach for ventilators could help kids breathe easier
- Study tests safer intubation for obese patients: to ventilate or not?
- New airway device could make anesthesia safer by allowing easy tube swaps
- Global experts aim to settle debate on ICU airway care
- Bacterial lysate shows promise in preventing infant wheeze after bronchiolitis