New computer tool aims to keep Kids' diaphragms strong on ventilators

NCT ID NCT03266016

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a computer program called REDvent that helps doctors set ventilators to match a child's natural breathing effort. The goal was to prevent the diaphragm from weakening while on a breathing machine. Researchers enrolled 248 children with lung disease who needed ventilation. The program used real-time measurements to adjust support, and the team tracked muscle strength and time on the ventilator.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Computerized ventilator protocol (REDvent)

What this could lead to

If successful, this approach could reduce the time children spend on ventilators and lower the risk of breathing muscle weakness.

What could go wrong

This is a Phase II trial with a moderate sample size; results may not confirm benefit in larger studies. The intervention is complex and may not work for all children.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diaphragm disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States