Bacterial lysate shows promise in preventing infant wheeze after bronchiolitis
NCT ID NCT05064631
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether a bacterial lysate (Broncho Vaxom) can prevent wheezing in infants who were hospitalized for severe bronchiolitis. 173 infants received either the lysate or a placebo for up to 24 months. The goal was to see if the treatment reduces the number of wheeze episodes in the first year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bacterial lysate (Broncho Vaxom)
What this could lead to
If it works, this could point toward a simple way to prevent wheezing and asthma in infants after severe bronchiolitis.
What could go wrong
This is a small, early-phase trial (phase 2) with only 173 infants. The treatment may not reduce wheeze episodes, and long-term benefits are uncertain.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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King's College Hospital NHS Foundation Trust
London, SE5 9RS, United Kingdom
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Royal London Hospital
London, E1 1FR, United Kingdom
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University Hospital Southampton NHS Foundation Trust
Southampton, SO16 6YD, United Kingdom