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Could vitamin d levels predict wheezing after bronchiolitis?

NCT ID NCT07700134

Ongoing Knowledge-focused Sponsor: National and Kapodistrian University of Athens Source: ClinicalTrials.gov ↗

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study investigates whether vitamin D levels, genetic variations in the vitamin D receptor, and changes in immune cell mitochondria can help predict which children will develop recurrent wheezing after a bout of bronchiolitis. Researchers will measure these markers in children under 2 hospitalized with bronchiolitis and compare them to healthy controls, then follow the children for 36 months to track wheezing episodes. The goal is to identify early biomarkers that could guide future prevention or treatment strategies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could identify biomarkers that predict which children are at risk for recurrent wheezing after bronchiolitis, potentially pointing toward preventive strategies.
What could go wrong
This is an observational study, not a treatment trial. It may find no clear link, and any identified biomarkers would need further validation before clinical use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute bronchiolitis bronchiolitis Respiratory Sounds

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHIOLITIS ACUTE RSV WHEEZING

Contacts and locations

Locations

  • "Aghia Sofia" Children's Hospital

    Athens, Attica, 11527, Greece

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